Iron-catalyzed one-pot tandem oxidation/acylation/dearomatization of biaryl ynones with benzyl alcohols: access to diversified acylated spiro[5.5]trienones

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-01-30 DOI:10.1016/j.tetlet.2025.155469

Dong Xia , Yanfeng Miao , Hongjian Ji , Wenchao Yang , Yun Shi

引用次数: 0

Abstract

A new iron-catalyzed tandem cyclization and 6-exo-trig dearomatization reaction of biaryl ynones with readily available benzyl alcohols was developed. In the presence of Fe(acac)₃ and tert-butyl hydroperoxide,a variety of acylated spiro[5.5]trienones were prepared through cascade oxidation/acylation/dearomatization process using benzyl alcohols as acylation reagent.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.