Advantages of electrochemically deposited bioceramic-coating on magnesium implant for anti-corrosion and bone regeneration

IF 5.7 2区材料科学 Q2 CHEMISTRY, PHYSICAL

Surfaces and Interfaces Pub Date : 2025-02-02 DOI:10.1016/j.surfin.2025.105936

Seo-young kim, Yu-kyoung kim, Yong-seok Jang, Min-ho Lee

{"title":"Advantages of electrochemically deposited bioceramic-coating on magnesium implant for anti-corrosion and bone regeneration","authors":"Seo-young kim, Yu-kyoung kim, Yong-seok Jang, Min-ho Lee","doi":"10.1016/j.surfin.2025.105936","DOIUrl":null,"url":null,"abstract":"<div><div>Magnesium implants offer the advantages of biodegradability and absorbability after implantation in bone fractures. However, they cause delayed bone regeneration owing to their fast biodegradation rates.</div><div>To address this issue, we attempted to utilize the bioactivity of bioceramic coatings and anti-corrosion property by doping Zn ions onto Mg implant surfaces. Zn-doped CaP bioceramic precipitation was induced on magnesium surfaces via electrochemical deposition in a mixed electrolyte of Ca(NO<sub>3</sub>)<sub>2</sub> and NH<sub>4</sub>H<sub>2</sub>PO<sub>4</sub> with varying concentrations of Zn(NO<sub>3</sub>)<sub>2</sub>. As a result, in an electrolyte containing a low concentration of Zn(NO<sub>3</sub>)<sub>2</sub>, a uniform film layer, consisting of hydroxyapatite (HA) and calcium zinc phosphate hydrate (CZPD) bioceramics, was formed with approximately 30 μm of thickness. This layer improved the corrosion resistance of the Mg surface in simulated body fluids and promoted the formation of bioactive substrates. Higher concentrations of Zn(NO<sub>3</sub>)<sub>2</sub> in the electrolyte led to an enhanced corrosion resistance with increasing Ca(OH)<sub>2</sub> precipitation. However, corrosion products were formed instead of bioactive substrates. Therefore, it was demonstrated that appropriate Zn(NO<sub>3</sub>)<sub>2</sub> addition during electrochemical deposition induced stable osteoblast attachment and uniform formation of a new bone layer, delayed biodegradation with excellent corrosion resistance, and promoted bone regeneration through the formation of bioactive substrates during implantation.</div></div>","PeriodicalId":22081,"journal":{"name":"Surfaces and Interfaces","volume":"59 ","pages":"Article 105936"},"PeriodicalIF":5.7000,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surfaces and Interfaces","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S246802302500197X","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Magnesium implants offer the advantages of biodegradability and absorbability after implantation in bone fractures. However, they cause delayed bone regeneration owing to their fast biodegradation rates.

To address this issue, we attempted to utilize the bioactivity of bioceramic coatings and anti-corrosion property by doping Zn ions onto Mg implant surfaces. Zn-doped CaP bioceramic precipitation was induced on magnesium surfaces via electrochemical deposition in a mixed electrolyte of Ca(NO₃)₂ and NH₄H₂PO₄ with varying concentrations of Zn(NO₃)₂. As a result, in an electrolyte containing a low concentration of Zn(NO₃)₂, a uniform film layer, consisting of hydroxyapatite (HA) and calcium zinc phosphate hydrate (CZPD) bioceramics, was formed with approximately 30 μm of thickness. This layer improved the corrosion resistance of the Mg surface in simulated body fluids and promoted the formation of bioactive substrates. Higher concentrations of Zn(NO₃)₂ in the electrolyte led to an enhanced corrosion resistance with increasing Ca(OH)₂ precipitation. However, corrosion products were formed instead of bioactive substrates. Therefore, it was demonstrated that appropriate Zn(NO₃)₂ addition during electrochemical deposition induced stable osteoblast attachment and uniform formation of a new bone layer, delayed biodegradation with excellent corrosion resistance, and promoted bone regeneration through the formation of bioactive substrates during implantation.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Surfaces and Interfaces Chemistry-General Chemistry

CiteScore

8.50

自引率

6.50%

发文量

753

审稿时长

35 days

期刊介绍： The aim of the journal is to provide a respectful outlet for ''sound science'' papers in all research areas on surfaces and interfaces. We define sound science papers as papers that describe new and well-executed research, but that do not necessarily provide brand new insights or are merely a description of research results. Surfaces and Interfaces publishes research papers in all fields of surface science which may not always find the right home on first submission to our Elsevier sister journals (Applied Surface, Surface and Coatings Technology, Thin Solid Films)