Le défi de l’obésité dans les maladies psychiatriques

IF 0.5 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Nutrition Clinique et Metabolisme Pub Date : 2023-12-01 DOI:10.1016/S0985-0562(24)00016-5

Sébastien Guillaume , Patrick Ritz

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引用次数: 0

Abstract

Overweight and obesity are common in severe and chronic psychiatric disorders. Up to 50% of patients suffering from schizophrenia or bipolar disorder are obese. The mortality rate is 4.5 times higher than in the general population, mainly due to metabolic and cardiovascular disorders. Numerous factors, interconnected by vicious circles of mutually reinforcing adverse physiological adaptations, contribute to this association. Close collaboration between mental health and somatic health specialists is essential for coordinated, individualized care. This will involve an integrative assessment to understand the factors behind the genesis of obesity, the consequences in terms of co-morbidity, and the possibilities of therapeutic options, including the ability to access treatment. Treatment paths should also include early detection of subjects at risk of weight gain, close monitoring of the metabolic effects of psychotropic drugs, hygienic-dietary measures and non-drug interventions. In addition, the role of bariatric surgery and obesity drugs requires more detailed investigations in these patients.

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肥胖对精神疾病的挑战

超重和肥胖在严重和慢性精神疾病中很常见。高达50%的精神分裂症或双相情感障碍患者患有肥胖症。其死亡率是一般人口的4.5倍，主要是由于代谢和心血管疾病。许多因素，相互加强不利的生理适应的恶性循环相互联系，促成了这种联系。精神卫生和躯体卫生专家之间的密切合作对于协调、个性化的护理至关重要。这将涉及一项综合评估，以了解肥胖成因背后的因素，合并症的后果，以及治疗选择的可能性，包括获得治疗的能力。治疗途径还应包括早期发现有体重增加危险的受试者，密切监测精神药物的代谢影响，卫生-饮食措施和非药物干预措施。此外，减肥手术和减肥药的作用需要在这些患者中进行更详细的调查。©2023法国社会组织（SFNCM）。Elsevier Masson SAS出版。版权所有。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition Clinique et Metabolisme 医学-内分泌学与代谢

CiteScore

0.80

自引率

16.70%

发文量

216

审稿时长

78 days

期刊介绍： Nutrition Clinique et Métabolisme is the journal of the French-speaking Society of Enteral and Parenteral Nutrition. Associating clinicians, biologists, pharmacists, and fundamentalists, the articles presented in the journal concern man and animals, and deal with organs and cells. The goal is a better understanding of the effects of artificial nutrition and human metabolism. Original articles, general reviews, update articles, technical notes and communications are published, as well as editorials and case reports.