Withania somnifera (Ashwagandha) supplementation: a review of its mechanisms, health benefits, and role in sports performance.

IF 3.9 2区医学 Q2 NUTRITION & DIETETICS

Nutrition & Metabolism Pub Date : 2025-02-05 DOI:10.1186/s12986-025-00902-7

Mateusz Sprengel, Radosław Laskowski, Zbigniew Jost

引用次数: 0

Abstract

In recent years Withania somnifera (Ashwagandha) gained a lot of interest as an adaptogen, aiding sleep, stress management and presenting health and sports-related benefits. Although clinical effects have been previously reviewed, the specific mechanism of Ashwagandha's action and its impact on different aspects of physical performance, body composition, as well as medical effects need more thorough analysis. Therefore, this narrative review delves into the available research examining the effects of Ashwagandha supplementation on such qualities as: strength, endurance, power, recovery, muscle mass, body fat, fertility, anxiety, metabolic health and aging, with additional focus on potential mechanisms underlying these effects. Moreover, we propose future perspectives based on the gaps observed in Ashwagandha research up to date.

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Withania somnifera （Ashwagandha）补充剂：其机制、健康益处和运动表现作用的综述。

近年来，作为一种适应原，藜草（Ashwagandha）获得了很多关注，它有助于睡眠、压力管理，并对健康和运动有好处。虽然之前已有临床效果的综述，但Ashwagandha作用的具体机制及其对身体机能、身体成分和医疗效果的不同方面的影响需要更深入的分析。因此，这篇叙述性综述深入研究了现有的研究，研究了Ashwagandha补充剂对以下品质的影响：力量、耐力、力量、恢复、肌肉量、体脂、生育能力、焦虑、代谢健康和衰老，并额外关注了这些影响的潜在机制。此外，我们根据迄今为止在阿什瓦甘达研究中观察到的差距提出了未来的展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition & Metabolism 医学-营养学

CiteScore

8.40

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Nutrition & Metabolism publishes studies with a clear focus on nutrition and metabolism with applications ranging from nutrition needs, exercise physiology, clinical and population studies, as well as the underlying mechanisms in these aspects. The areas of interest for Nutrition & Metabolism encompass studies in molecular nutrition in the context of obesity, diabetes, lipedemias, metabolic syndrome and exercise physiology. Manuscripts related to molecular, cellular and human metabolism, nutrient sensing and nutrient–gene interactions are also in interest, as are submissions that have employed new and innovative strategies like metabolomics/lipidomics or other omic-based biomarkers to predict nutritional status and metabolic diseases. Key areas we wish to encourage submissions from include: -how diet and specific nutrients interact with genes, proteins or metabolites to influence metabolic phenotypes and disease outcomes; -the role of epigenetic factors and the microbiome in the pathogenesis of metabolic diseases and their influence on metabolic responses to diet and food components; -how diet and other environmental factors affect epigenetics and microbiota; the extent to which genetic and nongenetic factors modify personal metabolic responses to diet and food compositions and the mechanisms involved; -how specific biologic networks and nutrient sensing mechanisms attribute to metabolic variability.