The prevalence and risk factors for peripheral nerve injury following arthroplasty: a systematic review and meta-analysis.

IF 2.8 3区 医学 Q1 ORTHOPEDICS
Jianchun Qiu, Xiaohong Liao, Ruiming Deng
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引用次数: 0

Abstract

Objective: To assess the prevalence and identify the risk factors for peripheral nerve injury (PNI) following arthroplasty through a systematic review and meta-analysis.

Methods: PubMed, Embase, and the Cochrane Library were searched for observational studies investigating the prevalence and risk factors for PNI following arthroplasty. Prevalence data for PNI following arthroplasty were extracted and pooled using a random-effects model, with results presented as pooled prevalence with 95% CI. ORs and 95% CIs for identified risk factors were calculated. Subgroup analyses were conducted based on age, study type, sample size, arthroplasty site, region, and others. Publication bias was assessed using funnel plots and Egger's test, and sensitivity analyses were performed.

Results: After screening, a total of 21 studies were included in the meta-analysis. The pooled prevalence of PNI was 0.7% (95% CI: 0.006-0.009) with significant heterogeneity (I² = 99%). The prevalence of PNI following arthroplasty was found to be more likely as a result of several identified factors, including spinal conditions (ORs = 2.269, 95% CI 1.625-3.170), postoperative anemia (ORs = 1.370, 95% CI 1.149-1.633), mechanical complications (ORs = 1.791, 95% CI 1.118-2.868) and hypothyroidism (ORs = 1.189, 95% CI 1.054-1.341).

Conclusions: The pooled prevalence of PNI was approximately 0.7%. Furthermore, we identified potential risk factors for PNI following arthroplasty, including spinal conditions, postoperative anemia, mechanical complications, and hypothyroidism. Our findings emphasize the importance of recognizing these risk factors in the perioperative management of arthroplasty patients.

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来源期刊
CiteScore
4.10
自引率
7.70%
发文量
494
审稿时长
>12 weeks
期刊介绍: Journal of Orthopaedic Surgery and Research is an open access journal that encompasses all aspects of clinical and basic research studies related to musculoskeletal issues. Orthopaedic research is conducted at clinical and basic science levels. With the advancement of new technologies and the increasing expectation and demand from doctors and patients, we are witnessing an enormous growth in clinical orthopaedic research, particularly in the fields of traumatology, spinal surgery, joint replacement, sports medicine, musculoskeletal tumour management, hand microsurgery, foot and ankle surgery, paediatric orthopaedic, and orthopaedic rehabilitation. The involvement of basic science ranges from molecular, cellular, structural and functional perspectives to tissue engineering, gait analysis, automation and robotic surgery. Implant and biomaterial designs are new disciplines that complement clinical applications. JOSR encourages the publication of multidisciplinary research with collaboration amongst clinicians and scientists from different disciplines, which will be the trend in the coming decades.
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