Exploring ABI5 regulation: Post-translational control and cofactor interactions in ABA signaling

IF 6.2 1区生物学 Q1 PLANT SCIENCES

The Plant Journal Pub Date : 2025-02-06 DOI:10.1111/tpj.17232

Chang Du, Haiyan Bai, Yujie Yan, Yurui Liu, Xiangying Wang, Zhonghui Zhang

{"title":"Exploring ABI5 regulation: Post-translational control and cofactor interactions in ABA signaling","authors":"Chang Du, Haiyan Bai, Yujie Yan, Yurui Liu, Xiangying Wang, Zhonghui Zhang","doi":"10.1111/tpj.17232","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Abscisic acid insensitive 5 (ABI5) is a pivotal transcription factor in abscisic acid (ABA) signaling, playing an essential role in plant growth and responses to abiotic stress. This key regulator is subject to multifaceted regulation, especially on post-translational mechanisms. Recent research has shed light on the post-translational regulation of ABI5, encompassing both post-translational modifications (PTMs) and the modulation of its transcriptional activity. In this review, we provide a comprehensive overview of the current knowledge surrounding the post-translational regulation of ABI5, along with the influence of various cofactors on its transcriptional activity and protein stability. The potential biological roles of PTMs of ABI5 in the context of ABA signaling and plant stress responses are also explored. As ABI5 is one of the most extensively studied proteins in the context of plant ABA signaling and environmental stress responses, a sophisticated and precise understanding of the regulatory mechanisms that govern ABI5 is not only beneficial for its application in genetic engineering but also helpful for our exploration in the fundamental principles of post-translational regulation.</p>\n </div>","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"121 3","pages":""},"PeriodicalIF":6.2000,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Plant Journal","FirstCategoryId":"2","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/tpj.17232","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Abscisic acid insensitive 5 (ABI5) is a pivotal transcription factor in abscisic acid (ABA) signaling, playing an essential role in plant growth and responses to abiotic stress. This key regulator is subject to multifaceted regulation, especially on post-translational mechanisms. Recent research has shed light on the post-translational regulation of ABI5, encompassing both post-translational modifications (PTMs) and the modulation of its transcriptional activity. In this review, we provide a comprehensive overview of the current knowledge surrounding the post-translational regulation of ABI5, along with the influence of various cofactors on its transcriptional activity and protein stability. The potential biological roles of PTMs of ABI5 in the context of ABA signaling and plant stress responses are also explored. As ABI5 is one of the most extensively studied proteins in the context of plant ABA signaling and environmental stress responses, a sophisticated and precise understanding of the regulatory mechanisms that govern ABI5 is not only beneficial for its application in genetic engineering but also helpful for our exploration in the fundamental principles of post-translational regulation.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

The Plant Journal 生物-植物科学

CiteScore

13.10

自引率

4.20%

发文量

415

审稿时长

2.3 months

期刊介绍： Publishing the best original research papers in all key areas of modern plant biology from the world"s leading laboratories, The Plant Journal provides a dynamic forum for this ever growing international research community. Plant science research is now at the forefront of research in the biological sciences, with breakthroughs in our understanding of fundamental processes in plants matching those in other organisms. The impact of molecular genetics and the availability of model and crop species can be seen in all aspects of plant biology. For publication in The Plant Journal the research must provide a highly significant new contribution to our understanding of plants and be of general interest to the plant science community.