Non-aggregated ruthenium naphthalocyanine enabling homogeneous carbene insertion into N-H bonds at low catalyst loading

Abstract

The novel ruthenium octa-n-butoxy-naphthalocyanine complex was shown to retain essentially monomeric state in diluted solutions. It was succesfully applied as homogeneous catalyst for the carbene insertion to N-H bonds of amines with various substitution pattern providing high yields of glycine derivatives.