A 3-in-1 wearable and implantable biopatch for integrated in-body energy harvesting, sensing, and self-powered diabetic wound treatments

IF 16.8 1区材料科学 Q1 CHEMISTRY, PHYSICAL

Nano Energy Pub Date : 2025-02-05 DOI:10.1016/j.nanoen.2025.110743

Jianglong Kong , Runxuan Chu , Meiru Mao , Hongrui Yu , Jiawen Liu , Yuting Sun , Xiaohan Ge , Zixin Jin , Weimin Huang , Na Hu , Yi Wang

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Abstract

The integration of energy generators, implantable and wearable sensors, and therapeutic devices holds great promise for the future of health care. In this study, a 3-in-1 multifunctional biopatch (M-BioP) capable of harvesting energy from body and organ movements was developed. M-BioP, which is enhanced with 2D materials, demonstrates excellent output performance and durability, efficiently converting harvested energy into electrical stimulation for sensing and therapeutic applications. M-BioP can promote the migration and proliferation of fibroblasts in vitro. The near-infrared (NIR)-assisted M-BioP exhibited photothermal antibacterial effects on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa with high efficiency and a long duration. By promoting collagen deposition, angiogenesis, and M2 polarization of macrophages at the wound site, the NIR-assisted M-BioP accelerates the healing of diabetic wounds infected with bacteria; this represents the first instance of an implanted patch for antibacterial therapy as well as in-body energy harvesting, presenting novel opportunities for future medical innovations.

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来源期刊

Nano Energy CHEMISTRY, PHYSICAL-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

30.30

自引率

7.40%

发文量

1207

审稿时长

23 days

期刊介绍： Nano Energy is a multidisciplinary, rapid-publication forum of original peer-reviewed contributions on the science and engineering of nanomaterials and nanodevices used in all forms of energy harvesting, conversion, storage, utilization and policy. Through its mixture of articles, reviews, communications, research news, and information on key developments, Nano Energy provides a comprehensive coverage of this exciting and dynamic field which joins nanoscience and nanotechnology with energy science. The journal is relevant to all those who are interested in nanomaterials solutions to the energy problem. Nano Energy publishes original experimental and theoretical research on all aspects of energy-related research which utilizes nanomaterials and nanotechnology. Manuscripts of four types are considered: review articles which inform readers of the latest research and advances in energy science; rapid communications which feature exciting research breakthroughs in the field; full-length articles which report comprehensive research developments; and news and opinions which comment on topical issues or express views on the developments in related fields.