Physical activity and male reproductive function.

Abstract

Fecundity is declining in humans, which is partly due to male infertility. Poor sperm parameters, the main contributors to male infertility, are associated with sedentary, unhealthy lifestyle and poor dietary habits. Long periods of sedentary work lead to visceral adiposity and persistently elevated scrotal temperatures, which adversely affect spermatogenesis. Apart from increasing scrotal temperatures, excessive visceral adiposity exacerbates adipocyte dysfunction with increased pro-inflammatory adipokine release, like leptin. These, together with the increased scrotal temperature, are responsible for the poor sperm quality. The importance of regular physical activity in male fertility remains a matter of debate, as not all forms of exercises have been found to benefit sperm function. Sperm parameters are, nevertheless, somewhat better in active than in sedentary men. It now appears that low-to-moderate intensity exercises are more beneficial for male reproductive health than high-intensity exercises, which have a negative effect on spermatozoa. Low-to-moderate intensity exercises, in general, improve the overall organ-system function in the body, improve the management of body weight and oxidative stress, consequently improving sperm parameters. The detrimental effects of high-intensity exercises on spermatozoa result from disruption in the hypothalamus-pituitary-gonadal-axis, raised testicular temperature and increased oxidative stress. It, therefore, seems that not all types of exercises are beneficial for male reproductive health. Although some low-to-moderate intensity exercises improve male reproductive function, there remains a need to identify the best form of low-to-moderate intensity exercises, particularly those that do not increase testicular temperature or oxidative stress, to help maintain normal body weight and male reproductive health.