Efficacy of Electrofulguration for Women with recurrent urinary tract infection on quality of life and sexual function.

IF 1.5 4区 医学 Q3 UROLOGY & NEPHROLOGY
Cüneyd Sevinç, Orkunt Özkaptan, Cengiz Çanakcı, Uğur Yılmaz, Alkan Çubuk
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Abstract

Introduction The primary objective of the study was to assess the impact of EF in women with rUTI on quality of life and sexual health. Methods This prospective observational clinical study included 152 patients women who underwent EF because of rUTI and were followed for a minimum of 18 months. The SF-12 questionnaire and the Female Sexual Function Index (FSFI) are used to evaluate quality of life and sexual dysfunction. The Patient Global Impression of Improvement (PGI-I) scale was assessed to evaluate subjective cure. Endoscopic success was defined as complete resolution of previous lesions without new lesions seen during cystoscopy Clinical success was defined as no urinary tract infections at the last follow-up; improvement as 1-2 treated infections/year; and failure as ≥3 treated infections/year. Chi-square test, Wilcoxon, and Student's paired t-test were used. Results Seventy patients (52.6%) were defined as cured at least a 1-year follow-up. The subjective cure rate was 71.4% (N = 95) according to PGI-I scores. Women had significantly higher average FSFI scores (P=0.001) in the one-year postoperative assessment. Overall, pathological mental health and physical health scores were significantly higher after the intervention (P=0.00). Thirty-one (23.3%) patients improved clinically with <3 infections per year, and 32 (24.1%) patients failed with >3 infections per year. A total of 97 (74.4%) patients had endoscopic resolution postoperative evaluation. Conclusion EF resulted in clinical cure and improvement in the large majority of the patients. A significant proportion of the patients demonstrated enhanced sexual function and quality of life.

引言 本研究的主要目的是评估尿路感染女性患者接受 EF 对生活质量和性健康的影响。方法 这项前瞻性临床观察研究纳入了 152 名因急性尿路感染而接受 EF 治疗的女性患者,并对她们进行了至少 18 个月的随访。采用 SF-12 问卷和女性性功能指数 (FSFI) 评估生活质量和性功能障碍。患者全球改善印象量表(PGI-I)用于评估主观治愈情况。内镜治疗成功的定义是膀胱镜检查时未发现新病灶,之前的病灶完全消退 临床治疗成功的定义是最后一次随访时未发现尿路感染;好转的定义是每年治疗 1-2 次感染;失败的定义是每年治疗≥3 次感染。采用卡方检验、Wilcoxon 检验和学生配对 t 检验。结果 70 名患者(52.6%)在至少 1 年的随访中被定义为治愈。根据 PGI-I 评分,主观治愈率为 71.4%(95 人)。在术后一年的评估中,女性的 FSFI 平均得分明显更高(P=0.001)。总体而言,干预后病理心理健康和身体健康评分明显更高(P=0.00)。31名患者(23.3%)的临床症状有所改善,每年有3例感染。共有 97 名(74.4%)患者在术后评估中获得了内镜治疗。结论 EF 使绝大多数患者的临床症状得到治愈和改善。相当一部分患者的性功能和生活质量都得到了改善。
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来源期刊
Urologia Internationalis
Urologia Internationalis 医学-泌尿学与肾脏学
CiteScore
3.30
自引率
6.20%
发文量
94
审稿时长
3-8 weeks
期刊介绍: Concise but fully substantiated international reports of clinically oriented research into science and current management of urogenital disorders form the nucleus of original as well as basic research papers. These are supplemented by up-to-date reviews by international experts on the state-of-the-art of key topics of clinical urological practice. Essential topics receiving regular coverage include the introduction of new techniques and instrumentation as well as the evaluation of new functional tests and diagnostic methods. Special attention is given to advances in surgical techniques and clinical oncology. The regular publication of selected case reports represents the great variation in urological disease and illustrates treatment solutions in singular cases.
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