Is there still hesitancy towards SARS-CoV-2 vaccination among people with neurological disease- a survey of the NeuroCOVID-19 task force of the European Academy of Neurology.

IF 2.7 4区 医学 Q2 CLINICAL NEUROLOGY
Neurological Sciences Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI:10.1007/s10072-025-08017-w
Sonja Hochmeister, Martin Rakusa, Elena Moro, Daniel Bereczki, Francesco Cavallieri, Alessandra Fanciulli, Saša R Filipović, Alla Guekht, Raimund Helbok, Filippo Martinelli Boneschi, Serefnur Özturk, Alberto Priori, Barbara Willekens, Dauren Ramankulov, Johann Sellner
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引用次数: 0

Abstract

Background: An online 3-item survey was sent to the European Academy of Neurology (EAN) community and inquired about the persistence of SARS-CoV-2 vaccination skepticism and the underlying thoughts and factors restricting vaccine use among patients with neurological conditions.

Results: We obtained 616 responses from 84 countries, predominantly from Europe. In the view of the treating neurologist, patients with multiple sclerosis (MS), neuroimmunological disorders (ND), and chronic neurological infections continued to have high levels of skepticism toward SARS-CoV-2 vaccination. Patients with MS/ND were quoted as the most hesitant group, with 60% of the respondents sharing this impression. The patient group perceived as most confident towards immunization against COVID-19 and with the lowest level of distrust towards the vaccine were those with sleep disorders. For all other conditions, perceived distrust ranged between 42 and 52%. Fear of adverse events of vaccination or disease reactivation was perceived by 87% of patients with MS/ND and more than 70% of patients with stroke/vascular neurology, neuromuscular disorders, chronic neurological infections, and peripheral neuropathy. Patients with sleep disorders (54%), autonomic disorders (46%), movement disorders (43%), and dementia (43%) were sensed as less fearful of vaccine-related adverse events.

Conclusion: Despite the large body of evidence proving the efficacy and safety of SARS-CoV-2 vaccination, patients with certain neurological disorders still have a surprisingly high percentage of distrust and fear of adverse events. Our observations emphasize the importance of continuous evidence-based information delivery and patient education by treating neurologists.

神经系统疾病患者对SARS-CoV-2疫苗接种是否仍然犹豫不决——欧洲神经病学学会神经covid -19工作组的一项调查。
背景:向欧洲神经病学学会(EAN)社区发送了一份3项在线调查,询问神经系统疾病患者对SARS-CoV-2疫苗接种持怀疑态度的持续性以及限制疫苗使用的潜在想法和因素。结果:我们获得了来自84个国家的616份回复,主要来自欧洲。在治疗神经科医生看来,患有多发性硬化症(MS)、神经免疫疾病(ND)和慢性神经系统感染的患者仍然对SARS-CoV-2疫苗接种持高度怀疑态度。多发性硬化症/ND患者被认为是最犹豫的群体,60%的受访者有这种印象。对COVID-19免疫接种最有信心、对疫苗不信任程度最低的患者群体是睡眠障碍患者。在所有其他情况下,感知到的不信任在42%到52%之间。87%的MS/ND患者和超过70%的卒中/血管神经病学、神经肌肉疾病、慢性神经感染和周围神经病变患者感到害怕接种疫苗或疾病再激活的不良事件。睡眠障碍(54%)、自主神经障碍(46%)、运动障碍(43%)和痴呆(43%)患者被认为对疫苗相关不良事件的恐惧程度较低。结论:尽管有大量证据证明了SARS-CoV-2疫苗接种的有效性和安全性,但某些神经系统疾病患者对不良事件的不信任和恐惧比例仍然高得惊人。我们的观察强调了持续的循证信息传递和治疗神经科医生的患者教育的重要性。
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来源期刊
Neurological Sciences
Neurological Sciences 医学-临床神经学
CiteScore
6.10
自引率
3.00%
发文量
743
审稿时长
4 months
期刊介绍: Neurological Sciences is intended to provide a medium for the communication of results and ideas in the field of neuroscience. The journal welcomes contributions in both the basic and clinical aspects of the neurosciences. The official language of the journal is English. Reports are published in the form of original articles, short communications, editorials, reviews and letters to the editor. Original articles present the results of experimental or clinical studies in the neurosciences, while short communications are succinct reports permitting the rapid publication of novel results. Original contributions may be submitted for the special sections History of Neurology, Health Care and Neurological Digressions - a forum for cultural topics related to the neurosciences. The journal also publishes correspondence book reviews, meeting reports and announcements.
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