Impact of cognitive fatigue on balance in individuals with multiple sclerosis without cognitive impairment.

IF 1.7 4区医学 Q3 CLINICAL NEUROLOGY

Neurological Research Pub Date : 2025-03-01 Epub Date: 2025-02-04 DOI:10.1080/01616412.2025.2462733

Kübra Turan, Ayla Fil Balkan, Elçin Özçelik Eroğlu, Songül Aksoy, Nazire Pınar Acar Özen, Aslı Tuncer, Yeliz Salcı

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引用次数: 0

Abstract

Purpose: This study aims to examine the impact of cognitive fatigue on balance among individuals with multiple sclerosis (MS) without cognitive impairment.

Method: A total 50 individuals with MS aged 20-50 years, without cognitive impairment and with an Expanded Disability Status Scale (EDSS) score of 0-4, participated in the study. Participants were randomly assigned to either a control group (CG) or a study group (SG). The CG rested for 30 minutes, while the SG engaged in cognitive activities lasting 30-45 minutes to induce cognitive fatigue. Cognitive fatigue was assessed using the Visual Analog Scale (VAS) before and after the tasks. Balance was evaluated using clinical tests: the Functional Reach Test (FRT) and the Single Leg Stance Test (SLST), as well as laboratory assessments including the Modified Clinical Test of Sensory Integration and Balance (mCTSIB) and Limits of Stability (LOS) with static posturography.

Results: Within-group analyses showed a significant increase in cognitive fatigue on the VAS in the SG (p < 0.001). In the mCTSIB, the SG showed significant changes in firm/eyes open, foam/eyes open, and composite scores, while between-group differences were observed only in firm/eyes open and foam/eyes open conditions (p < 0.005). No significant differences were found between groups in LOS, FRT, or SLST outcomes (p > 0.05).

Conclusion: In individuals with MS, the impact observed only in the eyes-open static balance condition suggests that dynamic balance and eyes-closed static balance parameters rely more on automatic mechanisms compared to the eyes-open condition and are not influenced by cognitive fatigue.

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无认知障碍的多发性硬化症患者认知疲劳对平衡的影响。

目的：本研究旨在探讨认知疲劳对无认知障碍的多发性硬化症（MS）患者平衡能力的影响。方法：50例年龄20 ~ 50岁，无认知功能障碍，EDSS评分0 ~ 4分的MS患者参与研究。参与者被随机分配到对照组（CG）或研究组（SG）。CG休息30分钟，SG进行30-45分钟的认知活动，诱导认知疲劳。使用视觉模拟量表（VAS）评估任务前后的认知疲劳。使用临床测试评估平衡：功能到达测试（FRT）和单腿站立测试（SLST），以及实验室评估，包括改进的感觉整合和平衡临床测试（mCTSIB）和稳定性极限（LOS）与静态姿势记录。结果：组内分析显示，SG组VAS认知疲劳评分显著增加（p p p > 0.05）。结论：在MS个体中，仅在睁眼静态平衡状态下观察到的影响表明，与睁眼相比，动态平衡和闭眼静态平衡参数更依赖于自动机制，不受认知疲劳的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurological Research 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

116

审稿时长

5.3 months

期刊介绍： Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields. The scope of the journal includes: •Stem cell applications •Molecular neuroscience •Neuropharmacology •Neuroradiology •Neurochemistry •Biomathematical models •Endovascular neurosurgery •Innovation in neurosurgery.