Receipt of fluoroquinolone prophylaxis is not associated with development of vancomycin-resistant Enterococcus colonization during pediatric hematopoietic cell transplantation.

Abstract

Fluoroquinolones are used to prevent bloodstream infections in pediatric hematopoietic cell transplant (HCT) recipients. We performed a retrospective cohort study in 799 pediatric HCT patients to evaluate the association between fluoroquinolone prophylaxis and VRE colonization. Propensity score analyses were performed. Fluoroquinolone prophylaxis was not associated with VRE colonization.