{"title":"An Imidazo-Pyridin-Derived Fluorescent Probe for Monitoring Hydrogen Sulfide in Chinese Medicinal Materials.","authors":"Lisi Mao, Xionggao Han, Honghua Wu, Lingyan Xu, Hui Zheng, Fengping Wang, Chaoyue Wang, Jingyan Xu","doi":"10.1007/s10895-024-04083-z","DOIUrl":null,"url":null,"abstract":"<p><p>Herein, an imidazo-pyridin-derived fluorescent probe ImPy-HS was developed for monitoring the hydrogen sulfide (H<sub>2</sub>S) level in the water decoction of Chinese medicinal materials. Under the excitation at 355 nm, ImPy-HS exhibited the obvious fluorescence response at 490 nm. The detection system with ImPy-HS showed the advantages including relatively high sensitivity, high selectivity, and high steadiness. Especially, in the water decoction of Chinese medicinal materials with H<sub>2</sub>S from both addition and excessive fumigation then reduction, ImPy-HS achieved the monitoring of the H<sub>2</sub>S level. ImPy-HS also realized the imaging of both exogenous and endogenous H<sub>2</sub>S as well as the water decoction-treated affection. The information here was meaningful for studying the quality control of Chinese medicinal materials.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-024-04083-z","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
Herein, an imidazo-pyridin-derived fluorescent probe ImPy-HS was developed for monitoring the hydrogen sulfide (H2S) level in the water decoction of Chinese medicinal materials. Under the excitation at 355 nm, ImPy-HS exhibited the obvious fluorescence response at 490 nm. The detection system with ImPy-HS showed the advantages including relatively high sensitivity, high selectivity, and high steadiness. Especially, in the water decoction of Chinese medicinal materials with H2S from both addition and excessive fumigation then reduction, ImPy-HS achieved the monitoring of the H2S level. ImPy-HS also realized the imaging of both exogenous and endogenous H2S as well as the water decoction-treated affection. The information here was meaningful for studying the quality control of Chinese medicinal materials.
期刊介绍：
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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