Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI.

IF 1.1 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Acta radiologica Pub Date : 2025-02-04 DOI:10.1177/02841851241313021

Theresa Mokry, Judith Pantke, Hans-Ulrich Kauczor, Frederik B Laun, Heinz-Peter Schlemmer, Tristan A Kuder, Sebastian Bickelhaupt

{"title":"Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI.","authors":"Theresa Mokry, Judith Pantke, Hans-Ulrich Kauczor, Frederik B Laun, Heinz-Peter Schlemmer, Tristan A Kuder, Sebastian Bickelhaupt","doi":"10.1177/02841851241313021","DOIUrl":null,"url":null,"abstract":"Background: Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries.Purpose: To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries.Material and methods: This prospective, single-centre study consisted of repeated 1.5-T and 3-T examinations in 30 female volunteers (mean age=27.9 years, age range=20.3-45.2 years) from July 2017 to September 2019. Multi b-value DWI 0, 50, 100, 800, 1500, 2000 s/mm2 was acquired over three timepoints during the menstrual cycle. Ovaries were segmented at b = 1500 s/mm2. Median apparent diffusion coefficient (ADC) and advanced kurtosis parameters Dapp and Kapp were calculated. Statistical analysis was performed with the variations of diffusivity variables being compared between 1.5-T and 3-T MRI using a Mann-Whitney rank-sum test.Results: Median ADC and Dapp (µm²/ms) did not statistically differ. Median ADC were 1.509 (range=1.371-1.610), 1.619 (range=1.463-1.747), and 1.511 (range=1.423-1.639) at 1.5 T; 1.542 (range=1.428-1.682), 1.658 (range=1.510-1.806), and 1.572 (range=1.455-1.709) at 3 T (P = 0.14, 0.19, and 0.07), whereas median Dapp were 2.024 (range=1.913-2.152), 2.192 (range=2.010-2.327), and 2.045 (range=1.958-2.170) at 1.5 T; 2.013 (range=1.952-2.188), 2.179 (range=2.018-2.327), and 2.082 (range=1.959-2.194) at 3 T (P = 0.77, 0.99, and 0.34) for timepoints 1, 2, and 3, respectively. Statistical comparison of Kapp revealed significant differences for all timepoints: 0.629 (range=0.595-0.652), 0.604 (range=0.574-0.651), and 0.622 (range=0.581-0.664) at 1.5 T; 0.601 (range=0.563-0.626), 0.567 (range=0.526-0.633), and 0.599 (range=0.541-0.650) at 3 T (P < 0.001, 0.005, and 0.03).Conclusion: Diffusivity mapping in the ovaries provides similar absolute median diffusion values, but statistically significant differences in absolute kurtosis values between 1.5 T and 3 T.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241313021"},"PeriodicalIF":1.1000,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/02841851241313021","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries.

Purpose: To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries.

Material and methods: This prospective, single-centre study consisted of repeated 1.5-T and 3-T examinations in 30 female volunteers (mean age=27.9 years, age range=20.3-45.2 years) from July 2017 to September 2019. Multi b-value DWI 0, 50, 100, 800, 1500, 2000 s/mm² was acquired over three timepoints during the menstrual cycle. Ovaries were segmented at b = 1500 s/mm². Median apparent diffusion coefficient (ADC) and advanced kurtosis parameters D_app and K_app were calculated. Statistical analysis was performed with the variations of diffusivity variables being compared between 1.5-T and 3-T MRI using a Mann-Whitney rank-sum test.

Results: Median ADC and D_app (µm²/ms) did not statistically differ. Median ADC were 1.509 (range=1.371-1.610), 1.619 (range=1.463-1.747), and 1.511 (range=1.423-1.639) at 1.5 T; 1.542 (range=1.428-1.682), 1.658 (range=1.510-1.806), and 1.572 (range=1.455-1.709) at 3 T (P = 0.14, 0.19, and 0.07), whereas median D_app were 2.024 (range=1.913-2.152), 2.192 (range=2.010-2.327), and 2.045 (range=1.958-2.170) at 1.5 T; 2.013 (range=1.952-2.188), 2.179 (range=2.018-2.327), and 2.082 (range=1.959-2.194) at 3 T (P = 0.77, 0.99, and 0.34) for timepoints 1, 2, and 3, respectively. Statistical comparison of K_app revealed significant differences for all timepoints: 0.629 (range=0.595-0.652), 0.604 (range=0.574-0.651), and 0.622 (range=0.581-0.664) at 1.5 T; 0.601 (range=0.563-0.626), 0.567 (range=0.526-0.633), and 0.599 (range=0.541-0.650) at 3 T (P < 0.001, 0.005, and 0.03).

Conclusion: Diffusivity mapping in the ovaries provides similar absolute median diffusion values, but statistically significant differences in absolute kurtosis values between 1.5 T and 3 T.

查看原文本刊更多论文

背景：目的：评估扫描仪场强对卵巢盆腔 MRI 定量弥散变量的影响：这项前瞻性、单中心研究包括2017年7月至2019年9月对30名女性志愿者（平均年龄=27.9岁，年龄范围=20.3-45.2岁）重复进行1.5T和3T检查。在月经周期的三个时间点采集了0、50、100、800、1500、2000 s/mm2的多b值DWI。卵巢在 b = 1500 s/mm2 时被分割。计算中位表观扩散系数（ADC）和高级峰度参数 Dapp 和 Kapp。使用 Mann-Whitney 秩和检验对 1.5-T 和 3-T MRI 的扩散变量变化进行比较，并进行统计分析：结果：中位 ADC 和 Dapp（µm²/ms）没有统计学差异。1.5 T 的 ADC 中位数分别为 1.509（范围=1.371-1.610）、1.619（范围=1.463-1.747）和 1.511（范围=1.423-1.639）；1.542（范围=1.428-1.682）、1.658（范围=1.510-1.806）和1.572（范围=1.455-1.709）（P=0.14、0.19和0.07），而Dapp中值为2.1.5T时分别为2.024（范围=1.913-2.152）、2.192（范围=2.010-2.327）和2.045（范围=1.958-2.170）；3T时分别为2.013（范围=1.952-2.188）、2.179（范围=2.018-2.327）和2.082（范围=1.959-2.194）（P=0.77、0.99和0.34）。对 Kapp 的统计比较显示，所有时间点均存在显著差异：在 1.5 T 时为 0.629（范围=0.595-0.652）、0.604（范围=0.574-0.651）和 0.622（范围=0.581-0.664）；在 3 T 时为 0.601（范围=0.563-0.626）、0.567（范围=0.526-0.633）和 0.599（范围=0.541-0.650）（P 结论）：卵巢弥散分布图提供了相似的绝对中位弥散值，但 1.5 T 和 3 T 的绝对峰度值在统计学上存在显著差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Acta radiologica 医学-核医学

CiteScore

2.70

自引率

0.00%

发文量

170

审稿时长

3-8 weeks

期刊介绍： Acta Radiologica publishes articles on all aspects of radiology, from clinical radiology to experimental work. It is known for articles based on experimental work and contrast media research, giving priority to scientific original papers. The distinguished international editorial board also invite review articles, short communications and technical and instrumental notes.