Individual variability in lactate response to cycling prescribed using physiological thresholds and peak work rate: a crossover within-participant repeated measures study.

IF 2.8 3区 医学 Q2 PHYSIOLOGY
European Journal of Applied Physiology Pub Date : 2025-07-01 Epub Date: 2025-02-05 DOI:10.1007/s00421-025-05711-7
Lauren J Pacitti, Kaitlyn E Shikaze, Nia Simpson-Stairs, Jonathan Stringer, Brendon J Gurd
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Abstract

Purpose: (1) To determine if the blood lactate concentration ([BLa]) response is a repeatable individual trait, and (2) To examine whether threshold-based prescription (THR) reduces interindividual variability in [BLa] response compared to traditional (maximally anchored) exercise prescription (TRAD).

Method: A crossover within-participant repeated measures design was used to assess [BLa] during the TRAD and THR exercise in 17 participants (9 M/8F). Participants initially undertook an incremental test to exhaustion to determine peak work rate (WRpeak), a lactate threshold (LT) test and a critical power (CP) test. All baseline tests were repeated twice. Participants then completed 6 15-min bouts of continuous cycling at 65%WRpeak (TRAD; 3 bouts) and 80% of the difference (Δ80) between LT and CP (THR; 3 bouts). [BLa] response was measured at 10 and 15 min of exercise.

Results: Across individuals, there was a wide range in [BLa] response, but within individual responses were repeatable. [BLa] ranges and mean individual 90% confidence interval width (CIw) were as follows: TRAD@10 min = 2.1-9.7 mmol, CIw = 0.5 mmol, THR@10 min = 3.4-9.3 mmol, CIw = 0.6 mmol, TRAD@15 min = 2.2-9.9 mmol, CIw = 0.6 mmol, THR@15 min = 3.6-12.3 mmol, CIw = 0.7 mmol. Levene's tests revealed no significant differences in the variability of [BLa] response between TRAD and THR at 10 min (F = 0.523, p = 0.475) or 15 min (F = 0.351, p = 0.558) of exercise.

Conclusion: Our results demonstrate that true interindividual variability in the [BLa] response to exercise exists, but failed to confirm that variability in [BLa] response is reduced with the use of THR.

使用生理阈值和峰值工作速率规定的乳酸反应的个体差异:参与者重复测量的交叉研究。
目的:(1)确定血乳酸浓度([BLa])反应是否是可重复的个体特征;(2)研究与传统(最大锚定)运动处方(TRAD)相比,基于阈值的处方(THR)是否降低了[BLa]反应的个体间变异性。方法:采用参与者内交叉重复测量设计评估17名参与者(9 M/8F)在TRAD和THR锻炼期间的[BLa]。参与者最初进行了累加测试,以确定峰值工作率(WRpeak),乳酸门槛(LT)测试和临界功率(CP)测试。所有基线测试重复两次。然后,参与者以65%的wr峰值(TRAD)完成6次15分钟的连续骑行;3回合)和LT与CP (THR;3次)。在运动10和15分钟时测量[BLa]反应。结果:在个体间,[BLa]的反应范围较大,但个体间的反应是可重复的。[BLa]范围和平均个体90%置信区间宽度(CIw)如下:TRAD@10 min = 2.1-9.7 mmol, CIw = 0.5 mmol, THR@10 min = 3.4-9.3 mmol, CIw = 0.6 mmol, TRAD@15 min = 2.2-9.9 mmol, CIw = 0.6 mmol, THR@15 min = 3.6-12.3 mmol, CIw = 0.7 mmol。Levene的测试显示,在运动10分钟(F = 0.523, p = 0.475)或15分钟(F = 0.351, p = 0.558)时,TRAD和THR之间的[BLa]反应变异性无显著差异。结论:我们的研究结果表明,运动后[BLa]反应的个体间变异性确实存在,但未能证实使用THR会降低[BLa]反应的变异性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.00
自引率
6.70%
发文量
227
审稿时长
3 months
期刊介绍: The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.
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