Individual variability in lactate response to cycling prescribed using physiological thresholds and peak work rate: a crossover within-participant repeated measures study.

IF 2.8 3区 医学 Q2 PHYSIOLOGY
Lauren J Pacitti, Kaitlyn E Shikaze, Nia Simpson-Stairs, Jonathan Stringer, Brendon J Gurd
{"title":"Individual variability in lactate response to cycling prescribed using physiological thresholds and peak work rate: a crossover within-participant repeated measures study.","authors":"Lauren J Pacitti, Kaitlyn E Shikaze, Nia Simpson-Stairs, Jonathan Stringer, Brendon J Gurd","doi":"10.1007/s00421-025-05711-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>(1) To determine if the blood lactate concentration ([BLa]) response is a repeatable individual trait, and (2) To examine whether threshold-based prescription (THR) reduces interindividual variability in [BLa] response compared to traditional (maximally anchored) exercise prescription (TRAD).</p><p><strong>Method: </strong>A crossover within-participant repeated measures design was used to assess [BLa] during the TRAD and THR exercise in 17 participants (9 M/8F). Participants initially undertook an incremental test to exhaustion to determine peak work rate (WRpeak), a lactate threshold (LT) test and a critical power (CP) test. All baseline tests were repeated twice. Participants then completed 6 15-min bouts of continuous cycling at 65%WRpeak (TRAD; 3 bouts) and 80% of the difference (Δ80) between LT and CP (THR; 3 bouts). [BLa] response was measured at 10 and 15 min of exercise.</p><p><strong>Results: </strong>Across individuals, there was a wide range in [BLa] response, but within individual responses were repeatable. [BLa] ranges and mean individual 90% confidence interval width (CI<sub>w</sub>) were as follows: TRAD@10 min = 2.1-9.7 mmol, CI<sub>w</sub> = 0.5 mmol, THR@10 min = 3.4-9.3 mmol, CI<sub>w</sub> = 0.6 mmol, TRAD@15 min = 2.2-9.9 mmol, CI<sub>w</sub> = 0.6 mmol, THR@15 min = 3.6-12.3 mmol, CI<sub>w</sub> = 0.7 mmol. Levene's tests revealed no significant differences in the variability of [BLa] response between TRAD and THR at 10 min (F = 0.523, p = 0.475) or 15 min (F = 0.351, p = 0.558) of exercise.</p><p><strong>Conclusion: </strong>Our results demonstrate that true interindividual variability in the [BLa] response to exercise exists, but failed to confirm that variability in [BLa] response is reduced with the use of THR.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Applied Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00421-025-05711-7","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: (1) To determine if the blood lactate concentration ([BLa]) response is a repeatable individual trait, and (2) To examine whether threshold-based prescription (THR) reduces interindividual variability in [BLa] response compared to traditional (maximally anchored) exercise prescription (TRAD).

Method: A crossover within-participant repeated measures design was used to assess [BLa] during the TRAD and THR exercise in 17 participants (9 M/8F). Participants initially undertook an incremental test to exhaustion to determine peak work rate (WRpeak), a lactate threshold (LT) test and a critical power (CP) test. All baseline tests were repeated twice. Participants then completed 6 15-min bouts of continuous cycling at 65%WRpeak (TRAD; 3 bouts) and 80% of the difference (Δ80) between LT and CP (THR; 3 bouts). [BLa] response was measured at 10 and 15 min of exercise.

Results: Across individuals, there was a wide range in [BLa] response, but within individual responses were repeatable. [BLa] ranges and mean individual 90% confidence interval width (CIw) were as follows: TRAD@10 min = 2.1-9.7 mmol, CIw = 0.5 mmol, THR@10 min = 3.4-9.3 mmol, CIw = 0.6 mmol, TRAD@15 min = 2.2-9.9 mmol, CIw = 0.6 mmol, THR@15 min = 3.6-12.3 mmol, CIw = 0.7 mmol. Levene's tests revealed no significant differences in the variability of [BLa] response between TRAD and THR at 10 min (F = 0.523, p = 0.475) or 15 min (F = 0.351, p = 0.558) of exercise.

Conclusion: Our results demonstrate that true interindividual variability in the [BLa] response to exercise exists, but failed to confirm that variability in [BLa] response is reduced with the use of THR.

求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
6.00
自引率
6.70%
发文量
227
审稿时长
3 months
期刊介绍: The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信