Synthesis of novel peptide-based tetracarboxylate ligands for metal organic framework (MOF) systems and applications

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-02-01 DOI:10.1016/j.tet.2024.134387

Moustafa Hamaad, Rudolf J. Wehmschulte

引用次数: 0

Abstract

Novel peptide-based tetracarboxylate ligands that consist of a pair of isophthalate moieties (ditopic 1,3-benzene dicarboxylate groups) bridged together through their 5-position by a flexible peptide core spacer have been synthesized through solution-phase peptide synthesis based on Boc chemistry (Boc: tert-butyloxycarbonyl). The peptide spacer component of the ligands is based on Glycine-Glycine, Alanine-Glycine, Phenylalanine-Glycine, Tryptophan-Glycine, Serine-Glycine, Aspartic-Glycine dipeptides and the Glycine-Glycine-Glycine tripeptide. These novel linkers are potential candidates as key building blocks for the construction of biomimetic metal-organic frameworks (MOFs).

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.