Advancing quinoxaline chemistry: Sustainable and green synthesis using L-arabinose as a catalyst

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2024-12-01 DOI:10.1080/00397911.2024.2419861

Sandip J. Detke , Anuja D. Karwande , Sai Srinivas Ponugoti , Shreerang V. Joshi , Prashant S. Kharkar

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Abstract

In the present study, an innovative and eco-friendly methodology for synthesizing quinoxaline derivatives has been introduced, leveraging L-arabinose as a novel catalyst. This approach not only underscores the feasibility of green chemistry in synthesizing high-purity quinoxaline derivatives but also highlights the enhanced sustainability of the process. Detailed mechanistic investigations revealed the synergistic interactions between L-arabinose and the reactants, providing a deeper understanding of the catalytic process. The synthesized compounds, due to their unique structural and electronic properties, may find promising applications in life and material sciences such as optoelectronics. Furthermore, our environmental impact assessment demonstrated significant reduction in generated waste, solvent use, and overall carbon footprint, aligning with the global agenda for sustainable development. This research marks a significant step forward in quinoxaline chemistry, promoting the adoption of green synthesis pathways while reinforcing the principles of sustainable and environment-friendly chemical practices.

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推进喹啉化学：以l -阿拉伯糖为催化剂的可持续绿色合成

在本研究中，介绍了一种利用l -阿拉伯糖作为新型催化剂合成喹诺啉衍生物的创新和环保的方法。该方法不仅强调了绿色化学合成高纯度喹诺啉衍生物的可行性，而且强调了该过程的可持续性。详细的机理研究揭示了l -阿拉伯糖与反应物之间的协同相互作用，为催化过程提供了更深入的了解。合成的化合物由于其独特的结构和电子特性，在生命科学和材料科学（如光电子学）中有很好的应用前景。此外，我们的环境影响评估显示，产生的废物、溶剂的使用和总体碳足迹显著减少，符合全球可持续发展议程。本研究标志着喹诺啉化学向前迈出了重要一步，促进了绿色合成途径的采用，同时加强了可持续和环境友好的化学实践原则。

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.