Trends and perspectives on the ultrasound-assisted extraction of bioactive compounds using natural deep eutectic solvents

IF 8 2区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Current Opinion in Chemical Engineering Pub Date : 2025-01-10 DOI:10.1016/j.coche.2024.101088

Thiago C Pereira, Vinícius P Souza, Ana Paula F Padilha, Fabio A Duarte, Erico MM Flores

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Abstract

In recent years, the recovery of bioactive substances from biomass has been widely studied for obtaining high-value products, such as phenolic compounds and polyphenols. The ultrasound-assisted extraction (UAE) has gained recognition as an effective technique for extracting compounds with lower solvent, time, and energy requirements, compared to conventional processes (e.g. Soxhlet). The introduction of greener solvents for extraction procedures, such as natural deep eutectic solvents (NADES), arose as a safer option than conventional organic solvents like methanol. The synergy of UAE-NADES processes can provide extracts of biocompounds with enhanced total phenolic content and superior antioxidant activity compared to extracts with conventional solvents. Using different hydrogen bond acceptors and hydrogen bond donors for NADES synthesis can generate solvents suited to diverse applications. This review aims to briefly present the status of UAE-NADES applications published from 2021 to 2024, exploring their key uses and benefits.

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来源期刊

Current Opinion in Chemical Engineering BIOTECHNOLOGY & APPLIED MICROBIOLOGYENGINE-ENGINEERING, CHEMICAL

CiteScore

12.80

自引率

3.00%

发文量

114

期刊介绍： Current Opinion in Chemical Engineering is devoted to bringing forth short and focused review articles written by experts on current advances in different areas of chemical engineering. Only invited review articles will be published. The goals of each review article in Current Opinion in Chemical Engineering are: 1. To acquaint the reader/researcher with the most important recent papers in the given topic. 2. To provide the reader with the views/opinions of the expert in each topic. The reviews are short (about 2500 words or 5-10 printed pages with figures) and serve as an invaluable source of information for researchers, teachers, professionals and students. The reviews also aim to stimulate exchange of ideas among experts. Themed sections: Each review will focus on particular aspects of one of the following themed sections of chemical engineering: 1. Nanotechnology 2. Energy and environmental engineering 3. Biotechnology and bioprocess engineering 4. Biological engineering (covering tissue engineering, regenerative medicine, drug delivery) 5. Separation engineering (covering membrane technologies, adsorbents, desalination, distillation etc.) 6. Materials engineering (covering biomaterials, inorganic especially ceramic materials, nanostructured materials). 7. Process systems engineering 8. Reaction engineering and catalysis.