Transition-Metal-free Michael Addition/Denitrative cyclization of 2′-Nitrochalcones and thioacetamides for the synthesis of thioflavanones

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-01-04 DOI:10.1016/j.tetlet.2024.155451

Wenjun Wang, Yao Xu, Xiaoming Liao, Zhuoran Yang, Faxiu Feng, Xue Wang, Wenjuan Fan, Xiaoxiang Zhang

引用次数: 0

Abstract

A novel method for the preparation of thioflavanones from 2′-nitrochalcones and thioacetamides has been developed. The reaction achieved the dissociation of inert groups and employed the thioacetamide as an odorless sulfur source. The desired products were obtained in up to 86% yield under transition-metal-free conditions.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.