Development Progress of Radiotherapy Recommendations For Low-/Middle-Income Countries (LMICs) via Adapted Resource and Implementation Application (ARIA) Adapted Management Guidelines (AMGs)

IF 6.4 1区医学 Q1 ONCOLOGY

International Journal of Radiation Oncology Biology Physics Pub Date : 2025-02-03 DOI:10.1016/j.ijrobp.2024.11.041

B. Qureshi , K. Marcus , J. Parkes , N. Esiashvili , M. Riviello , M. Key

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引用次数: 0

Abstract

Objectives

To describe the development and current progress of the ARIA Guide AMG radiation oncology components (ROCs) for hodgkin lymphoma (HOD), low-grade glioma (LGG), unilateral retinoblastoma (RBU), and neuroblastoma (NBL).

Methods

The ARIA Guide AMGs are a systematically derived set of guidelines developed in four phases and adapted to all resource settings based on the input of global representative panels (GRPs) across all World Health Organization regions and World Bank income levels. The strategy, consensus, validation, and dissemination phases integrate existing evidence-based methods, rigorous consensus-based approaches via a classic Delphi process, and expert global representation.

Results

The ARIA Guide GRPs for these four cancer types include 34 radiation oncologists from 17 different countries who have contributed 294 specific comments during three rounds of structured, iterative reviews for HOD, LGG, RBU, and NBL AMGs resulting in 105 AMG radiotherapy integrations. The Delphi statements collectively facilitated agreeance for 18 key controversial radiotherapy areas. Eight more cancer types are currently in strategy phase. All ROCs included indications for radiation therapy (RT); timing of consult and therapy; quality assurance; importance of RT plan peer review; and special considerations. Unique sections included disease-specific technical guidance and, for RBU, the availability of brachytherapy.

Conclusion

Comprehensive global radiation oncology guidelines were uniquely derived and adapted across all resource settings in a clear, detailed, user-centric, and reasonable manner, enabling solutions for improving pediatric cancer care and closing the survival gap between resource settings. The draft (beta) versions in progress of select ARIA Guide AMGs are currently available at: ARIAguide.org (accessible both online and offline).

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来源期刊

International Journal of Radiation Oncology Biology Physics 医学-核医学

CiteScore

11.00

自引率

7.10%

发文量

2538

审稿时长

6.6 weeks

期刊介绍： International Journal of Radiation Oncology • Biology • Physics (IJROBP), known in the field as the Red Journal, publishes original laboratory and clinical investigations related to radiation oncology, radiation biology, medical physics, and both education and health policy as it relates to the field. This journal has a particular interest in original contributions of the following types: prospective clinical trials, outcomes research, and large database interrogation. In addition, it seeks reports of high-impact innovations in single or combined modality treatment, tumor sensitization, normal tissue protection (including both precision avoidance and pharmacologic means), brachytherapy, particle irradiation, and cancer imaging. Technical advances related to dosimetry and conformal radiation treatment planning are of interest, as are basic science studies investigating tumor physiology and the molecular biology underlying cancer and normal tissue radiation response.