{"title":"Recent advances in point-of-care testing (POCT) system based on upconversion luminescent materials","authors":"Shunuo Bian , Tao Jin , Wenqiang Lu","doi":"10.1016/j.mseb.2025.118049","DOIUrl":null,"url":null,"abstract":"<div><div>Point-of-care testing (POCT) technology has drawn significant attention due to its simplicity, rapidity, and low cost, without the need for expensive large-scale equipment and complex laboratory specimen processing and analysis. Upconversion nanoparticles (UCNPs) exhibit unique advantages including low background interference, excellent detection stability, and relatively low potential toxicity. As a result, POCT based on up-converting luminescent materials has gradually emerged as a hot research topic in recent years. This paper offers a comprehensive review of the current progress and applications of upconversion luminescent materials within the field of POCT. It places particular emphasis on exploring ways to design and enhance the structure of upconversion luminescent materials, aiming to further optimize POCT detection methodologies. A concise introduction to the current application status of upconversion luminescence-based POCT technology is provided, along with key points and solution ideas for the design and application of UCNPs nanocomposites in POCT.</div></div>","PeriodicalId":18233,"journal":{"name":"Materials Science and Engineering: B","volume":"314 ","pages":"Article 118049"},"PeriodicalIF":3.9000,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Science and Engineering: B","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0921510725000728","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Point-of-care testing (POCT) technology has drawn significant attention due to its simplicity, rapidity, and low cost, without the need for expensive large-scale equipment and complex laboratory specimen processing and analysis. Upconversion nanoparticles (UCNPs) exhibit unique advantages including low background interference, excellent detection stability, and relatively low potential toxicity. As a result, POCT based on up-converting luminescent materials has gradually emerged as a hot research topic in recent years. This paper offers a comprehensive review of the current progress and applications of upconversion luminescent materials within the field of POCT. It places particular emphasis on exploring ways to design and enhance the structure of upconversion luminescent materials, aiming to further optimize POCT detection methodologies. A concise introduction to the current application status of upconversion luminescence-based POCT technology is provided, along with key points and solution ideas for the design and application of UCNPs nanocomposites in POCT.
期刊介绍:
The journal provides an international medium for the publication of theoretical and experimental studies and reviews related to the electronic, electrochemical, ionic, magnetic, optical, and biosensing properties of solid state materials in bulk, thin film and particulate forms. Papers dealing with synthesis, processing, characterization, structure, physical properties and computational aspects of nano-crystalline, crystalline, amorphous and glassy forms of ceramics, semiconductors, layered insertion compounds, low-dimensional compounds and systems, fast-ion conductors, polymers and dielectrics are viewed as suitable for publication. Articles focused on nano-structured aspects of these advanced solid-state materials will also be considered suitable.