Iodine-catalyzed 1-Aryltriazene/CS2 duo for sonochemical synthesis of 3-Sulphenylindoles employing [BMIM(SO3H)][OTf] as recyclable promoting system.

Abstract

Iodine-catalyzed regioselective sulphenylation of various 3-substituted indoles using CS₂ as potential tool is demonstrated. An efficient and eco-friendly protocol has been developed to synthesize libraries of 3-sulphenyl indoles by employing CS₂ as sulphur coupling-linkage for various 1-aryltriaznes and indoles. Short reaction time, mild reaction conditions, recycle and reuse of ionic liquids (ILs) are the advantages of this methodology. A plausible reaction mechanism to narrate the exploitation of the catalytic and promoting systems is also highlights of this work.