Fertility treatment in women over 50: clinical and ethical considerations

Q3 Medicine

Obstetrics, Gynaecology and Reproductive Medicine Pub Date : 2025-01-01 DOI:10.1016/j.ogrm.2024.10.004

Sharon Tay, Peter Kerecsenyi, Raj Mathur

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引用次数: 0

Abstract

As more women prioritize education, career growth, and personal milestones, family planning is increasingly postponed until later in life. Contributing factors such as advanced education, career ambitions, highly effective contraceptive methods, and finding life partners at later stages have led to a growing interest in fertility treatments for women over 50. However, pursuing pregnancy at this age comes with significant clinical and ethical challenges. Women over 50 face elevated risks of aneuploidy, miscarriage, pre-eclampsia, gestational diabetes, and preterm delivery. These complications necessitate rigorous pre-treatment evaluations, enhanced monitoring protocols, and comprehensive care throughout pregnancy. Additionally, ethical concerns arise regarding the welfare of both mother and child, as well as the societal implications of offering fertility treatments to this demographic. This spotlight article explores the clinical risks, ethical considerations, and practical approaches to managing fertility treatment in women over 50.

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50岁以上妇女的生育治疗：临床和伦理考虑

随着越来越多的女性优先考虑教育、事业发展和个人里程碑，计划生育越来越被推迟到生命的后期。高等教育、事业抱负、高效避孕方法以及在晚年找到生活伴侣等因素导致50岁以上女性对生育治疗的兴趣日益浓厚。然而，在这个年龄继续怀孕会面临重大的临床和伦理挑战。50岁以上的女性患非整倍体、流产、先兆子痫、妊娠糖尿病和早产的风险较高。这些并发症需要严格的治疗前评估，加强监测方案，并在整个妊娠期间进行全面护理。此外，关于母亲和儿童的福利以及向这一人口提供生育治疗的社会影响的伦理问题也出现了。这篇重点文章探讨了50岁以上妇女生育治疗的临床风险、伦理考虑和实用方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetrics, Gynaecology and Reproductive Medicine Medicine-Obstetrics and Gynecology

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Obstetrics, Gynaecology and Reproductive Medicine is an authoritative and comprehensive resource that provides all obstetricians, gynaecologists and specialists in reproductive medicine with up-to-date reviews on all aspects of obstetrics and gynaecology. Over a 3-year cycle of 36 issues, the emphasis of the journal is on the clear and concise presentation of information of direct clinical relevance to specialists in the field and candidates studying for MRCOG Part II. Each issue contains review articles on obstetric and gynaecological topics. The journal is invaluable for obstetricians, gynaecologists and reproductive medicine specialists, in their role as trainers of MRCOG candidates and in keeping up to date across the broad span of the subject area.