Tissue engineering and biosensing applications of carbon-based nanomaterials

Seydanur Yücer , Begüm Sarac , Fatih Ciftci
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Abstract

Carbon nanomaterials (CNMs) have emerged as a transformative class of materials in the biomedical field, offering exceptional versatility and efficacy. This study highlights the unique mechanical, electrical, and biocompatible properties of CNMs that make them indispensable for applications such as drug delivery, biosensing, tissue engineering, and medical implants. Specifically, graphene's remarkable conductivity and mechanical strength enhance biosensor sensitivity and scaffold durability, while the tubular structure and functional surface chemistry of carbon nanotubes (CNTs) improve cellular interactions and mechanical stability in implants. Carbon dots, with their tunable fluorescence and high biocompatibility, are proving to be powerful agents for bioimaging, enabling more precise diagnostics.
This review consolidates recent advancements in the synthesis, functionalization, and biomedical integration of CNMs, emphasizing their role in next-generation applications. Notably, it addresses challenges related to scalable production and clinical safety, offering insights into overcoming these obstacles. The findings underline the transformative potential of CNMs in revolutionizing therapeutic and diagnostic approaches, paving the way for innovative solutions in healthcare.

Abstract Image

碳基纳米材料的组织工程和生物传感应用
碳纳米材料(CNMs)已成为生物医学领域的一种变革性材料,具有卓越的多功能性和功效。这项研究强调了CNMs独特的机械、电气和生物相容性,使其在药物输送、生物传感、组织工程和医疗植入物等应用中不可或缺。具体来说,石墨烯卓越的导电性和机械强度提高了生物传感器的灵敏度和支架的耐久性,而碳纳米管(CNTs)的管状结构和功能表面化学改善了植入物中的细胞相互作用和机械稳定性。碳点具有可调的荧光和高生物相容性,被证明是生物成像的强大试剂,可以实现更精确的诊断。本文综述了cnm的合成、功能化和生物医学集成方面的最新进展,强调了它们在下一代应用中的作用。值得注意的是,它解决了与规模化生产和临床安全相关的挑战,为克服这些障碍提供了见解。这些发现强调了cnm在革新治疗和诊断方法方面的变革潜力,为医疗保健领域的创新解决方案铺平了道路。
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来源期刊
Biomedical engineering advances
Biomedical engineering advances Bioengineering, Biomedical Engineering
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