Pd(II)-catalyzed hydroxy group directed synthesis of spiro-fused succinimide isochromenochromenones

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-01-30 DOI:10.1016/j.tetlet.2024.155434

Kongkona Gogoi , Bondana Bora , Geetika Borah , Sanjib Gogoi

引用次数: 0

Abstract

A new annulation reaction is developed for the synthesis of isochromene fused chromenones possessing spiro succinimides scaffold. In this hydroxyl group directed Pd(II)-catalyzed reaction, easily affordable 3-hydroxy-2-phenyl-chromenones and maleimides were used as the coupling partners to synthesize a wide range of the biologically relevant spirocyclic compounds.

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Pd（II）催化羟基定向合成螺融合琥珀酰亚胺异色胺酮

提出了一种新的环化反应，用于合成具有螺旋琥珀酰亚胺支架的等铬烯融合铬酮。在这个羟基导向的Pd（II）催化反应中，以价格低廉的3-羟基-2-苯基铬酮和马来酰亚胺作为偶联剂，合成了广泛的生物相关的螺环化合物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.