{"title":"Pd(II)-catalyzed hydroxy group directed synthesis of spiro-fused succinimide isochromenochromenones","authors":"Kongkona Gogoi , Bondana Bora , Geetika Borah , Sanjib Gogoi","doi":"10.1016/j.tetlet.2024.155434","DOIUrl":null,"url":null,"abstract":"<div><div>A new annulation reaction is developed for the synthesis of isochromene fused chromenones possessing spiro succinimides scaffold. In this hydroxyl group directed Pd(II)-catalyzed reaction, easily affordable 3-hydroxy-2-phenyl-chromenones and maleimides were used as the coupling partners to synthesize a wide range of the biologically relevant spirocyclic compounds.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"155 ","pages":"Article 155434"},"PeriodicalIF":1.5000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S004040392400529X","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A new annulation reaction is developed for the synthesis of isochromene fused chromenones possessing spiro succinimides scaffold. In this hydroxyl group directed Pd(II)-catalyzed reaction, easily affordable 3-hydroxy-2-phenyl-chromenones and maleimides were used as the coupling partners to synthesize a wide range of the biologically relevant spirocyclic compounds.
期刊介绍:
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.