Reductive heck cyclization and functionalyzation of 5-bromohomoadamant-4-ene carboxamide derivatives: The route to homoadamantene annulated heterocycles

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-01-30 DOI:10.1016/j.tetlet.2024.155431

Alexander N. Reznikov, Svetlana Yu. Vostruhina, Yury N. Klimochkin

引用次数: 0

Abstract

Palladium catalyzed intramolecular reductive Heck reaction and Heck/cyanation domino sequence of 5-bromohomoadamant-4-ene carboxamides are a convenient synthetic pathway that provides access to polycyclic annulated homoadamanthene derivatives with 5,6-dihydropyridin-2(1H)-one and 1,5-dihydro-2H-pyrrol-2-one cores.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.