{"title":"Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology","authors":"Xiujuan Li , Lun Liu , Song Wei","doi":"10.1016/j.jff.2024.106651","DOIUrl":null,"url":null,"abstract":"<div><div><em>Gynostemma pentaphyllum</em> (GP), recognized as both an edible vegetable and health tea, has been consumed for thousands of years. Chemical research indicates GP primarily contains active ingredients including saponins, polysaccharides, and flavonoids. Notably, saponins and polysaccharides are among the main active components of GP, which have been extensively utilized in medicine, food, healthcare, and cosmetics due to their bioactivities including anti-tumor, anti-oxidation, hypoglycemic, cardioprotective, neuroprotective and anti-inflammatory activities. We conducted searches in various online databases, including Elsevier, Springer, PubMed, Web of Science, and China Knowledge Network (CNKI), to gather literature on the traditional uses, structural characteristics, and biological activities of the active ingredients of GP published prior to October 2024. In this review, GP saponins were categorized and GP polysaccharides discovered in the last ten years were highlighted. Then, the bioactivities of GP are summarized and lays a solid foundation for its development as a functional health food.</div></div>","PeriodicalId":360,"journal":{"name":"Journal of Functional Foods","volume":"124 ","pages":"Article 106651"},"PeriodicalIF":3.8000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Functional Foods","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756464624006546","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Gynostemma pentaphyllum (GP), recognized as both an edible vegetable and health tea, has been consumed for thousands of years. Chemical research indicates GP primarily contains active ingredients including saponins, polysaccharides, and flavonoids. Notably, saponins and polysaccharides are among the main active components of GP, which have been extensively utilized in medicine, food, healthcare, and cosmetics due to their bioactivities including anti-tumor, anti-oxidation, hypoglycemic, cardioprotective, neuroprotective and anti-inflammatory activities. We conducted searches in various online databases, including Elsevier, Springer, PubMed, Web of Science, and China Knowledge Network (CNKI), to gather literature on the traditional uses, structural characteristics, and biological activities of the active ingredients of GP published prior to October 2024. In this review, GP saponins were categorized and GP polysaccharides discovered in the last ten years were highlighted. Then, the bioactivities of GP are summarized and lays a solid foundation for its development as a functional health food.
期刊介绍:
Journal of Functional Foods continues with the same aims and scope, editorial team, submission system and rigorous peer review. We give authors the possibility to publish their top-quality papers in a well-established leading journal in the food and nutrition fields. The Journal will keep its rigorous criteria to screen high impact research addressing relevant scientific topics and performed by sound methodologies.
The Journal of Functional Foods aims to bring together the results of fundamental and applied research into healthy foods and biologically active food ingredients.
The Journal is centered in the specific area at the boundaries among food technology, nutrition and health welcoming papers having a good interdisciplinary approach. The Journal will cover the fields of plant bioactives; dietary fibre, probiotics; functional lipids; bioactive peptides; vitamins, minerals and botanicals and other dietary supplements. Nutritional and technological aspects related to the development of functional foods and beverages are of core interest to the journal. Experimental works dealing with food digestion, bioavailability of food bioactives and on the mechanisms by which foods and their components are able to modulate physiological parameters connected with disease prevention are of particular interest as well as those dealing with personalized nutrition and nutritional needs in pathological subjects.