Xiaoming Yuan , Liying Fan , Hui Jin , Qingping Wu , Yu Ding
{"title":"Phage engineering using synthetic biology and artificial intelligence to enhance phage applications in food industry","authors":"Xiaoming Yuan , Liying Fan , Hui Jin , Qingping Wu , Yu Ding","doi":"10.1016/j.cofs.2025.101274","DOIUrl":null,"url":null,"abstract":"<div><div>The rapid advancements in synthetic biology and artificial intelligence (AI) technologies are continuously expanding the application of bacteriophages (phages); however, when it comes to the food industry, the development of phage applications has been relatively slow due to the complex and large-scale nature of the industry. In order to overcome these challenges, it is necessary to promote the development of phages with new technologies. Here, we introduce the latest synthetic biology methods and AI techniques that enhance phage functions and explore their potential in promoting phage applications in the food industry. Additionally, we discuss the potential of combining synthetic biology with AI technologies to overcome the unique challenges when applying phages in the food industry in the future.</div></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"62 ","pages":"Article 101274"},"PeriodicalIF":8.9000,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Food Science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214799325000049","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The rapid advancements in synthetic biology and artificial intelligence (AI) technologies are continuously expanding the application of bacteriophages (phages); however, when it comes to the food industry, the development of phage applications has been relatively slow due to the complex and large-scale nature of the industry. In order to overcome these challenges, it is necessary to promote the development of phages with new technologies. Here, we introduce the latest synthetic biology methods and AI techniques that enhance phage functions and explore their potential in promoting phage applications in the food industry. Additionally, we discuss the potential of combining synthetic biology with AI technologies to overcome the unique challenges when applying phages in the food industry in the future.
期刊介绍:
Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts.
Key Features:
Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science.
Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications.
Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.