Novel microfluidic chips integrated with smart devices for in situ detection of foodborne pathogenic bacteria

Abstract

The in situ detection of foodborne pathogens at the early stages of infection is crucial for preventing the further spread of pathogens. Currently, integrated microfluidic biosensors, combined with new materials and technologies, are widely used for the rapid detection of various pathogens in point-of-care-testing setting. Herein, we summarize recent advances in microfluidics-based biosensors for in situ detection of foodborne pathogens, with a focus on sample preprocessing, signal amplification, and the automation and intelligence of devices to improve detection sensitivity and performance. Furthermore, the future outlook of microfluidic biosensor-based assays for foodborne pathogens is also considered. The integrated microfluidic biosensors with convenient, rapid, sensitive, and cost-effective can provide a promising platform for early prevention and control of foodborne pathogen contamination.