Biological properties of bioactive compounds from brewers’ spent grain: current trends, challenges, and perspectives

IF 9.1 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Current Opinion in Food Science Pub Date : 2024-12-24 DOI:10.1016/j.cofs.2024.101268

Joncer Naibaho , Rizki Dwi Setiawan , Małgorzata Korzeniowska

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引用次数: 0

Abstract

Bioactive compounds from brewers’ spent grain (BSG) offer a high potential as a sustainable food and nutraceutical ingredient. Biological properties of those bioactive compounds strongly depend on the extraction methods applied. Protein from BSG has been well investigated for its mechanism of action in regulating systolic and diastolic blood pressure, inhibiting angiotensin-converting enzymes, as well as reducing triglyceride, cholesterol, and free fatty acids. Positively charged amino acids are aligned with anti-inflammatory action. Polyphenolic fractions maintain glucose metabolism enzymes, and several polyphenols are responsible for the prebiotic properties of BSG. Bioactivity of arabinoxylans depends on the ratio of arabinose and xylose and the presence of attached phenolic acids. Melanoidin, an antioxidant, is present in BSG as a result of the Maillard reaction. BSG contains minerals (calcium and ferric) and vitamin (B1) with considerably high bioaccessibility. More investigations are done towards simulation in the digestive system demonstrating its potential in the human digestive system. Toxicity assessment, as well as investigation on allergenic and antinutrient compounds, seems to be needed. Sustainable extraction techniques can be expected to enhance the bioactivity, bioavailability, and biosafety of bioactive compounds from BSG.

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啤酒废粮中生物活性化合物的生物学特性：当前趋势、挑战和前景

啤酒废旧谷物（BSG）的生物活性化合物作为一种可持续食品和营养保健成分具有很高的潜力。这些生物活性化合物的生物学特性在很大程度上取决于所采用的提取方法。BSG蛋白在调节收缩压和舒张压、抑制血管紧张素转换酶、降低甘油三酯、胆固醇和游离脂肪酸等方面的作用机制已经得到了很好的研究。带正电的氨基酸具有抗炎作用。多酚组分维持葡萄糖代谢酶，一些多酚负责BSG的益生元特性。阿拉伯木聚糖的生物活性取决于阿拉伯糖和木糖的比例以及附着的酚酸的存在。类黑素是一种抗氧化剂，由于美拉德反应而存在于BSG中。BSG含有矿物质（钙和铁）和维生素（B1），具有相当高的生物可及性。更多的研究是在消化系统模拟证明其在人类消化系统的潜力。似乎需要进行毒性评估，以及对致敏性和抗营养化合物的研究。可持续的提取技术有望提高BSG生物活性化合物的生物活性、生物利用度和生物安全性。

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来源期刊

Current Opinion in Food Science Agricultural and Biological Sciences-Food Science

CiteScore

18.40

自引率

4.00%

发文量

157

审稿时长

92 days

期刊介绍： Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts. Key Features: Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science. Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications. Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.