Dana El-Mughayyar MSc , Terrel Marshall BASc , Kenneth D’Souza PhD , Jeffrey B. MacLeod BSc , Amanda McCoy BNRN , Susan Morris BNRN Med , Meaghan Smith MNRN , Christopher W. White MD, PhD, FRCSC , Shreya Sarkar PhD , Keith R. Brunt PhD , Jean-François Légaré MD, FRCPSC, CIP
{"title":"Implementation of a Multidisciplinary Cardiogenic Shock Team in a Nonacademic Canadian Heart Centre: An Implementation Study","authors":"Dana El-Mughayyar MSc , Terrel Marshall BASc , Kenneth D’Souza PhD , Jeffrey B. MacLeod BSc , Amanda McCoy BNRN , Susan Morris BNRN Med , Meaghan Smith MNRN , Christopher W. White MD, PhD, FRCSC , Shreya Sarkar PhD , Keith R. Brunt PhD , Jean-François Légaré MD, FRCPSC, CIP","doi":"10.1016/j.cjco.2024.11.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>In this study we evaluated our ability to implement team-based cardiogenic shock (CS-Team), focussing on: 1) early screening; 2) CS-Team activation; and 3) use of invasive monitoring to guide therapy.</div></div><div><h3>Methods</h3><div>All patients admitted to the coronary care unit (CCU) over 12 months were screened for CS. A diagnosis of CS was made when both hypotension and hypoperfusion were present. The CS-Team was composed of the CCU attending, an interventional cardiologist, and a cardiac surgeon. Multivariate analysis was carried out with mortality as the outcome of interest.</div></div><div><h3>Results</h3><div>Screening was documented in 74% (1160 of 1562) of patients admitted to a critical care unit; of these, 1080 were not in CS. We identified 80 patients in CS (Society for Cardiovascular Angiography & Interventions [SCAI] stages C-E), which represented 6.9% of all screened patients. Patients in CS had significantly higher in-hospital mortality (35% vs 2%, <em>P</em> < 0.0001). CS-Team was activated in 35 of 80 patients (44%). CS-Team activation resulted in significantly greater use of invasive monitoring (pulmonary artery catheter [49% vs 7%, <em>P</em> < 0.0001], cardiac catheterization [94% vs 76%, <em>P</em> < 0.032], and mechanical circulatory support [51% vs 2%, <em>P</em> < 0.001]). Independent predictors of mortality were severity of CS (SCAI grades D or E) (odds ratio [OR] 18.78, 95% confidence interval [CI] 4.89-96.65) and age, in years (OR 1.07, 95% CI 1.01-1.14), whereas CS-Team was not predictive of mortality (OR 0.66, 95% CI 0.16-2.41).</div></div><div><h3>Conclusions</h3><div>We found that: 1) early screening by frontline staff was feasible but had limitations (26% screening failure); 2) CS-Team activation appeared discretionary (limited activation to 45% of patients); and 3) CS-Team activation resulted in a significant increase in the use of invasive monitoring that helped guide therapy.</div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"7 2","pages":"Pages 231-238"},"PeriodicalIF":2.5000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"CJC Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2589790X24005274","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Background
In this study we evaluated our ability to implement team-based cardiogenic shock (CS-Team), focussing on: 1) early screening; 2) CS-Team activation; and 3) use of invasive monitoring to guide therapy.
Methods
All patients admitted to the coronary care unit (CCU) over 12 months were screened for CS. A diagnosis of CS was made when both hypotension and hypoperfusion were present. The CS-Team was composed of the CCU attending, an interventional cardiologist, and a cardiac surgeon. Multivariate analysis was carried out with mortality as the outcome of interest.
Results
Screening was documented in 74% (1160 of 1562) of patients admitted to a critical care unit; of these, 1080 were not in CS. We identified 80 patients in CS (Society for Cardiovascular Angiography & Interventions [SCAI] stages C-E), which represented 6.9% of all screened patients. Patients in CS had significantly higher in-hospital mortality (35% vs 2%, P < 0.0001). CS-Team was activated in 35 of 80 patients (44%). CS-Team activation resulted in significantly greater use of invasive monitoring (pulmonary artery catheter [49% vs 7%, P < 0.0001], cardiac catheterization [94% vs 76%, P < 0.032], and mechanical circulatory support [51% vs 2%, P < 0.001]). Independent predictors of mortality were severity of CS (SCAI grades D or E) (odds ratio [OR] 18.78, 95% confidence interval [CI] 4.89-96.65) and age, in years (OR 1.07, 95% CI 1.01-1.14), whereas CS-Team was not predictive of mortality (OR 0.66, 95% CI 0.16-2.41).
Conclusions
We found that: 1) early screening by frontline staff was feasible but had limitations (26% screening failure); 2) CS-Team activation appeared discretionary (limited activation to 45% of patients); and 3) CS-Team activation resulted in a significant increase in the use of invasive monitoring that helped guide therapy.
在本研究中,我们评估了我们实施基于团队的心源性休克(CS-Team)的能力,重点是:1)早期筛查;2) CS-Team激活;3)利用有创监测指导治疗。方法对所有在冠心病监护室(CCU)住院12个月以上的患者进行CS筛查。当低血压和灌注不足同时出现时,诊断为CS。cs小组由CCU主治医师、一名介入心脏病专家和一名心脏外科医生组成。以死亡率作为关注的结果进行多变量分析。结果在1562例重症监护病房收治的患者中,有74%(1160例)进行了筛查;其中,1080个不在CS中。我们在心血管造影学会(Society for Cardiovascular Angiography &;干预[SCAI] C-E期,占所有筛查患者的6.9%。CS患者的住院死亡率明显更高(35% vs 2%, P <;0.0001)。CS-Team在80例患者中有35例(44%)被激活。CS-Team激活显著增加了有创监测(肺动脉导管)的使用[49% vs 7%, P <;0.0001],心导管插入术[94% vs 76%, P <;0.032]和机械循环支架[51% vs 2%, P <;0.001])。死亡率的独立预测因子是CS的严重程度(SCAI等级D或E)(比值比[or] 18.78, 95%可信区间[CI] 4.89-96.65)和年龄(or 1.07, 95% CI 1.01-1.14),而CS- team不能预测死亡率(or 0.66, 95% CI 0.16-2.41)。结论:1)一线人员早期筛查是可行的,但存在局限性(26%的筛查失败率);2) CS-Team激活似乎是随意的(45%的患者被限制激活);3) CS-Team激活导致侵入性监测的使用显著增加,有助于指导治疗。