Impact of SYNTAX score on 10-year outcomes in NSTE-ACS

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases Pub Date : 2025-01-01 DOI:10.1016/j.acvd.2024.10.074

F. Boukerche

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引用次数: 0

Abstract

Introduction

The very long-term prognostic effect of Syntax score on mortality is still undetermined.

Objective

The aim of this study was to investigate the long-term impact of SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score (SS) on mortality after invasive management in NSTE-ACS.

Method

A total of 292 consecutive patients (median age 62 years) with non-ST-elevation ACS were included, followed up for ≥ 10 years and were compared according to baseline SS.

Results

Among 292 patients with baseline SS, 227 patients (77.7%) had low SS (≤ 22), 32 (10.9%) had intermediate SS (23 to 32), and 33 (11.4%) had high SS (≥ 33). Cardiovascular mortality during the follow-up according to SS group was 15.9%, 31.3% and 54.5% (p < 10-3), respectively (Fig. 1). In multivariable Cox regression analysis, only age and Syntax score were independently associated with patient outcome. Syntax score ≥ 17 showed a sensitivity of 60.9%, specificity of 61.4%. The area under the ROC curve was 0.70 (95% confidence interval of 0.62–0.77).

Conclusion

The discriminative capacity of SS on long-term outcomes was relevant in NSTE-ACS patients.

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来源期刊

Archives of Cardiovascular Diseases 医学-心血管系统

CiteScore

4.40

自引率

6.70%

发文量

审稿时长

34 days

期刊介绍： The Journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles and editorials. Topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.