PRADOC: A multicentre randomized controlled trial to assess the efficiency of PRADO-IC, a nationwide pragmatic transition care management plan for hospitalized patients with heart failure in France

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases Pub Date : 2025-01-01 DOI:10.1016/j.acvd.2024.10.021

F. Roubille , J.-P. Labarre , M. Galinier , P. Berdague , N. Erika , Q. Delbaere , M. Robin , E. Prunet , F. Leclercq , J.-L. Pasquie , L. Papinaud , G. Mercier , J.-E. Ricci , G. Cayla

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引用次数: 0

Abstract

Introduction

The PRADO-IC is a transition care programme designed to improve the coordination of care between hospital and home that was generalized in France in 2014. The PRADO-IC consists of an administrative assistant who visits patients during hospitalization to schedule follow-up visits.

Objective

The aim of the present study was to evaluate the PRADO-IC programme based on the hypotheses provided by health authorities.

Method

The PRADOC study is a multicentre controlled randomized open-label mixed-method trial of the transition programme PRADO-IC vs. usual management in patients hospitalized with heart failure (SOC group; NCT03396081).

Results

A total of 404 patients were recruited between April 2018 and May 2021 (Fig. 1).

The mean patient age was 75 years (±12 years) in both groups. The two groups were well balanced regarding severity indices. At discharge, patients homogeneously received the recommended drugs. There was no difference between groups regarding hospitalizations for acute heart failure at 1 year, with 24.60% in the SOC group and 25.40% in the PRADO-IC group during the year following the index hospitalization [hazard ratio (HR) = 1.04, 95% confidence interval (CI) = 0.69–1.56; P = 0.85] or cardio-vascular mortality (HR = 0.67, 95% CI = 0.34–1.31; P = 0.24).

Conclusion

The PRADO-IC has not significantly improved clinical outcomes, though a trend toward reduced cardiovascular mortality is evident. These results will help in understanding how transitional care programmes remain to be integrated in current patients’ pathways, including telemonitoring, and to better tailor individualized approaches.

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来源期刊

Archives of Cardiovascular Diseases 医学-心血管系统

CiteScore

4.40

自引率

6.70%

发文量

审稿时长

34 days

期刊介绍： The Journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles and editorials. Topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.