Green synthesis of cerium oxide nanoparticles using Citrus nobilis Lour. Peel extract and evaluation of their potential as antibacterial and antioxidant agents

Q1 Environmental Science

Case Studies in Chemical and Environmental Engineering Pub Date : 2024-12-13 DOI:10.1016/j.cscee.2024.101062

Gusliani Eka Putri , Arniati Labanni , Syukri Arief , Putri Dafriani , Ika Yulia Darma , Sri Handayani , Widyastuti , Norzawani Jaffar , Marsal Mahmud , Ahmad Hafizullah Ritonga

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Abstract

Cerium oxide nanoparticles (CeO₂NPs) have been synthesized using Siam oranges (Citrus nobilis Lour.) peel extract as a capping agent with varied concentration. X-ray diffraction (XRD) analysis confirmed the formation of cubic fluorite crystal structured CeO₂NPs. Scanning electron microscope (SEM) and Transmission electron microscope (TEM) revealed that CeO₂NPs were quasi-spherical with sizes ranging from 10 to 40 nm. The most optimum concentration of siam orange peel extract was 10 %. IC50 value of 70.55 mg mL⁻¹ indicates a strong antioxidant activity of sample. Additionally, the antibacterial activity showed that CeO₂NPs were highly effective against S.aureus bacteria demonstrating their potential for biomedical applications.

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绿色合成氧化铈纳米颗粒的研究。果皮提取物及其抗菌和抗氧化潜力的评价

以不同浓度的暹罗橙子（Citrus nobilis Lour.）果皮提取物为封盖剂，合成了氧化铈纳米颗粒（CeO2NPs）。x射线衍射（XRD）分析证实形成了立方萤石晶体结构的CeO2NPs。扫描电镜（SEM）和透射电镜（TEM）分析表明，CeO2NPs为准球形，尺寸在10 ~ 40 nm之间。暹罗橙皮提取物的最佳浓度为10%。IC50值为70.55 mg mL−1，表明样品具有较强的抗氧化活性。此外，抗菌活性表明CeO2NPs对金黄色葡萄球菌非常有效，显示了其在生物医学上的应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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