Minimally invasive coronary artery bypass grafting via left anterior minithoracotomy: Setup, results, and evolution of a new surgical procedure

Abstract

Objective

Minimally invasive total arterial coronary artery bypass grafting offers the advantages of total arterial revascularization through an anterolateral minithoracotomy. However, the procedure is technically challenging and associated with a learning curve. The purpose of our study was to evaluate the progress and development of our program over an 8-year period.

Methods

We collected prospective data on all patients who underwent procedure at our institution from January 2015 to December 2023. Our program underwent several modifications during this study period, including optimization of surgical exposure using various available instruments, efficient intraoperative time management, utilization of a standard technique for all off-pump coronary artery bypass procedures, and close team member mentoring. Changes in quality control consisted of transitioning from routine postoperative coronary imaging to clinically indicated imaging. The influence of these interventions was assessed by focusing on in-hospital mortality as the primary end point, and operative time and perioperative myocardial infarction as secondary end points, over 2 time periods consisting of patients operated on during the first and second 4-year study period (Group 1, n = 137 and Group 2, n = 142).

Results

A total of 279 consecutive patients underwent elective, total arterial minimally invasive total arterial coronary artery bypass grafting at our institution over the study period. The mean age of patients was 66 ± 7 years, with 86% being men (n = 241) and 33.1% having diabetes (n = 77). Triple vessel disease was present in 53% of the cohort (n = 123) and left main disease was prevalent in 43% of patients (n = 101). The overall 30-day mortality was 0.4% (n = 1). Compared with the initial 4-year period, the rate of perioperative myocardial infarction decreased 3-fold (4.3% vs 1.4%; P = .1) and there was a statistically significant reduction in operating time (275 ± 59.5 and 246 ± 72.6 minutes; P < .001) in the most recent group of patients.

Conclusions

Total arterial minimally invasive total arterial coronary artery bypass grafting is a feasible surgical approach that can be performed with very good results, even during the initial learning curve phase. An evolving educational program can provide a smooth transition from off-pump coronary artery bypass grafting to minimally invasive total arterial coronary artery bypass grafting, when performed in selected patients in high-volume cardiac centers.