J.M. Martín de Bustamante González-Iglesias, A. Mendoza Martínez, G. Maortua Langdon, V. Jiménez Yuste
{"title":"Protocolo diagnóstico de la trombofilia","authors":"J.M. Martín de Bustamante González-Iglesias, A. Mendoza Martínez, G. Maortua Langdon, V. Jiménez Yuste","doi":"10.1016/j.med.2024.11.015","DOIUrl":null,"url":null,"abstract":"<div><div>Thrombophilias are inherited or acquired conditions that predispose individuals to the occurrence of thrombotic events. However, prothrombotic environmental risk factors and family history often play a more important role in the genesis and management of a thrombotic event than the presence of thrombophilia. Therefore, a thrombophilia study should be performed only in cases in which the therapeutic approach will be modified according to the results. This remains controversial at present; multiple clinical guidelines have altered their indications as the criteria for indefinite anticoagulation have changed. Currently, the indication for performing hereditary or acquired thrombophilia studies is reserved only for very specific situations.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 22","pages":"Pages 1323-1326"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine - Programa de Formación Médica Continuada Acreditado","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0304541224003019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Thrombophilias are inherited or acquired conditions that predispose individuals to the occurrence of thrombotic events. However, prothrombotic environmental risk factors and family history often play a more important role in the genesis and management of a thrombotic event than the presence of thrombophilia. Therefore, a thrombophilia study should be performed only in cases in which the therapeutic approach will be modified according to the results. This remains controversial at present; multiple clinical guidelines have altered their indications as the criteria for indefinite anticoagulation have changed. Currently, the indication for performing hereditary or acquired thrombophilia studies is reserved only for very specific situations.