Protocolo diagnóstico de las microangiopatías trombóticas

Abstract

Thrombotic microangiopathies (TMA) are a group of conditions characterized by the onset of microangiopathic hemolytic anemia, thrombocytopenia, and variable organ damage. The most important forms of TMA are thrombotic thrombocytopenic purpura (TTP), Shiga toxin-mediated TMA or typical hemolytic-uremic syndrome (HUS), and complement-mediated TMA or atypical HUS (aHUS). Due to its high morbidity and mortality, it is essential to establish an initial suspicion that allows for an early diagnosis and starting appropriate therapeutic measures