Trombofilia y trombosis

Abstract

Thrombophilia involves a predisposition to venous thromboembolism, which encompasses deep vein thrombosis and pulmonary embolism. It is an important cause of morbidity and mortality. The different thrombophilias can be classified as congenital or acquired. Among congenital thrombophilias, those that merit mention include factor V Leiden deficiency, prothrombin G20210A gene mutation, and the others described below. Among acquired thrombophilias, antiphospholipid syndrome merits mention, given its clinical relevance and prevalence. Its diagnostic criteria have recently been updated. It is essential to identify patients who have had thrombosis, and are thus candidates for thrombophilia screening, in order to reach an accurate diagnosis as soon as possible and establish early anticoagulant treatment to avoid late complications.