A renewable natural resource for ferulic acid; An efficient precursor in biotechnological production of vanillin and strategies to enhance the yield of bio-vanillin from ferulic acid - Review

IF 3.7 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Process Biochemistry Pub Date : 2025-02-01 DOI:10.1016/j.procbio.2024.12.012

Dhesiga Krishnan, Manian Rameshpathy

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Abstract

Vanillin is a primary flavoring aromatic component derived from Vanilla orchids and has extensive applications in the food, cosmetics, and pharmaceutical industries. Biotechnological approaches have emerged as a worthwhile alternative to natural vanillin's rising demand and cost. Ferulic acid is a suitable precursor for vanillin among various substrates (lignin, isoeugenol, eugenol). Agro-industrial wastes like rice bran, corn cob, and wheat bran are rich in ferulic acid and serve as a sustainable feedstock for vanillin production, concurrently supporting the concept of efficient waste disposal. The crucial steps to improve vanillin production from ferulic acid have been listed, including the usage of immobilized cells/enzymes in the bioconversion process, and their advantages over free cells. This review mainly delves into the natural sources of ferulic acid, and the microbes involved in bio-conversion, providing a comprehensive overview of advancements in biotechnological vanillin production.

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来源期刊

Process Biochemistry 生物-工程：化工

CiteScore

8.30

自引率

4.50%

发文量

374

审稿时长

53 days

期刊介绍： Process Biochemistry is an application-orientated research journal devoted to reporting advances with originality and novelty, in the science and technology of the processes involving bioactive molecules and living organisms. These processes concern the production of useful metabolites or materials, or the removal of toxic compounds using tools and methods of current biology and engineering. Its main areas of interest include novel bioprocesses and enabling technologies (such as nanobiotechnology, tissue engineering, directed evolution, metabolic engineering, systems biology, and synthetic biology) applicable in food (nutraceutical), healthcare (medical, pharmaceutical, cosmetic), energy (biofuels), environmental, and biorefinery industries and their underlying biological and engineering principles.