Topical bupivacaine effect on the response to awake extubation during emergence from general anesthesia in patients undergoing elective thyroidectomy. A randomized controlled study

Q2 Nursing
Shereen E. Abd Ellatif, Asmaa M. Galal Eldin, Rehab A. Wahdan
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引用次数: 0

Abstract

Background

A desirable combination of smooth extubation, even with prolonged extubation, and an easy maneuver to apply is difficult to achieve. This study aimed to evaluate the efficacy of 0.5% topical bupivacaine for reducing cough, postoperative sore throat, and hemodynamic fluctuations during extubation in patients undergoing thyroidectomy.

Methods

Forty-eight patients scheduled for thyroidectomy were randomly assigned to two equal groups (24 each): group (C) patients received 5 ml of 0.9% normal saline topically, and group (B) patients received 5 ml of 0.5% bupivacaine topically 15 min, around the tracheal tube, before the expected end of surgery, followed by manual ventilation to obtain air bubbles distributed throughout the entire airway mucosa. The primary outcomes were the incidence and grade of cough. The secondary outcomes were the incidence and degree of postoperative sore throat, extubation time, hemodynamic changes during extubation, and side effects.

Results

There was a statistically significant decrease in the incidence and the severity of cough in the bupivacaine group compared to the control group. Moreover, the severity of sore throat, as assessed by the VAS score, was lower in the bupivacaine group up to 12 hours postoperatively. The hemodynamic parameters significantly increased in the control group in the peri-extubation period compared to the bupivacaine group, with no difference in extubation time or side effects.

Conclusion

The use of topical bupivacaine around the ETT significantly reduced the incidence and severity of cough and postoperative sore throat with less hemodynamic fluctuations during the periextubation period in patients undergoing thyroidectomy.
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来源期刊
Perioperative Care and Operating Room Management
Perioperative Care and Operating Room Management Nursing-Medical and Surgical Nursing
CiteScore
1.30
自引率
0.00%
发文量
52
审稿时长
56 days
期刊介绍: The objective of this new online journal is to serve as a multidisciplinary, peer-reviewed source of information related to the administrative, economic, operational, safety, and quality aspects of the ambulatory and in-patient operating room and interventional procedural processes. The journal will provide high-quality information and research findings on operational and system-based approaches to ensure safe, coordinated, and high-value periprocedural care. With the current focus on value in health care it is essential that there is a venue for researchers to publish articles on quality improvement process initiatives, process flow modeling, information management, efficient design, cost improvement, use of novel technologies, and management.
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