Outcome of retrograde approach in management of chronic arterial occlusive disease of lower extremities

Tran Minh Bao Luan , Luong Viet Thang , Viet Huan Le
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Abstract

Introduction

Peripheral arterial disease or chronic arterial occlusive disease of lower extremities is a common problem, and in the advanced stages of the disease, if not re-vascularized, the rate of amputation and mortality can be as high as 43 % and 25 % respectively. Many studies also show that the rate of successful revascularization with an antegrade approach has a failure rate of 10–20 %. Therefore, the retrograde intervention technique was developed to increase the success rate of revascularization.

Objectives

Morphological classification of lesions and results of retrograde approach in the treatment of chronic arterial occlusive disease in lower extremities.

Method

Retrospective descriptive study. Thirty-five patients with 39 limbs received intervention with the retrograde approach at the Department of Thoracic and Vascular Surgery, University Medical Center. Ho Chi Minh City from February 2017 to December 2021.

Results

Most of the patients had multiple risk factors, including hypertension, diabetes, high grade on the Rutherford scale (79.5 % with Rutherford 5), and diffuse vascular disease (89.8 % GLASS III). Recanalization was technically successful in 84.6 % (33/39) limbs, and the patients with limb preservation rate at 6 months after intervention 88.5 %. Results at 12 and 24 months also confirm the procedure's feasibility and positive outlook. The local complication rate was low 7.7 % (3/39). There was 1 case that died 3 weeks after the intervention, not directly related to the procedure.

Conclusion

The retrograde technique is safe and effective in managing chronic total arterial occlusive disease of the lower limbs.
逆行入路治疗下肢慢性动脉闭塞性疾病的疗效
下肢外周动脉疾病或慢性动脉闭塞性疾病是一个常见的问题,在疾病的晚期,如果不进行血管重建,截肢率和死亡率分别可高达43%和25%。许多研究还表明,顺行入路血运重建成功率为10 - 20%。因此,为了提高血运重建的成功率,逆行介入技术应运而生。目的探讨逆行入路治疗下肢慢性动脉闭塞性疾病的病理形态分型及效果。方法回顾性描述性研究。大学医学中心胸血管外科35例患者39条肢体行逆行入路介入治疗。胡志明市2017年2月至2021年12月。结果大多数患者存在多重危险因素,包括高血压、糖尿病、Rutherford分级高(Rutherford 5)(79.5%)和弥漫性血管疾病(GLASS III)(89.8%), 84.6%(33/39)肢体技术上成功再通,干预后6个月肢体保存率88.5%。12个月和24个月的结果也证实了手术的可行性和积极的前景。局部并发症发生率低7.7%(3/39)。干预后3周死亡1例,与手术无直接关系。结论逆行手术治疗下肢慢性全动脉闭塞症安全有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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