Synovial sarcoma: A case report of first presentation at penoscrotal junction

Abstract

Synovial sarcoma is a rare malignant tumour that arises from mesenchymal origin. This case is about synovial sarcoma in unusual place, the scrotum and penile shaft. A 36-year-old man presented with a tender penoscrotal mass for 5 years. The patient underwent surgical resection of the mass. Histopathology revealed cellular spindle cell tumour arranged into interlacing fascicle, Immunohistochemistry analysis revealed a positive TLE-1, CD99, B-cell lymphoma 2 (BLC2), Focal cytokeratin and focal epithelial membrane antigen (EMA). In our case, the patient was aggressively treated with two surgical resections and still progressed and metastasized and continued progressing even after different chemotherapy regimens.