Advancements in NIR-based fluorescence imaging agents for oral oncology: A comprehensive review

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments Pub Date : 2025-01-08 DOI:10.1016/j.dyepig.2025.112637

Amal Adnan Ashour , Alaa Shafie , Ali Alqarni , Mohammed Fareed Felemban

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引用次数: 0

Abstract

NIR-based fluorescence imaging agents have emerged as a powerful diagnostic tool for early detection and monitoring of different types of cancer, offering high sensitivity, real-time visualization, and non-invasive assessment. This review explores recent advancements in NIR-based fluorescence imaging agents for oral oncology, focusing on the development and application of diverse imaging probes. Organic dyes, with their high fluorescence quantum yields and tunable spectral properties, have been extensively investigated for targeted imaging of cancer biomarkers. Additionally, nanomaterials such as quantum dots, gold nanoparticles, and carbon-based systems have demonstrated significant potential due to their unique optical properties, enhanced photostability, and ability to deliver multifunctional imaging and therapeutic capabilities. The integration of these innovative imaging agents with advanced fluorescence techniques has significantly improved the accuracy of oral cancer diagnosis and treatment monitoring.

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来源期刊

Dyes and Pigments 工程技术-材料科学：纺织

CiteScore

8.20

自引率

13.30%

发文量

933

审稿时长

33 days

期刊介绍： Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied. Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media. The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.