Fast-Acting and Skin-Compatible Antimicrobial Coating on Cotton Fabrics via In Situ Self-Assembly of Phosphine-Coordinated Copper Iodide Clusters

ACS Applied Engineering Materials Pub Date : 2024-11-27 DOI:10.1021/acsaenm.4c0054810.1021/acsaenm.4c00548

Adrielle Xianwen Chen, Devina Krystel Ravichandran Beins, Yue Wang, He-Kuan Luo*, Yi Yan Yang* and Ning Li*,

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Abstract

Cotton fabrics and textiles are ubiquitous in domestic, healthcare, and commercial settings, but they can harbor a multitude of disease-causing pathogens due to their lack of intrinsic antimicrobial properties. Here, we report a highly effective antiviral and antibacterial coating prepared in situ on commercial cotton fabrics by using phosphine-coordinated copper iodide clusters as the sole precursor. Self-assembled hexagonal nanodisks of [Cu₄I₄(TPP)₄] (TPP = triphenylphosphine) clusters formed a hydrophilic coating at only 0.36 wt % relative to the cotton substrate, but capable of eliminating >99.9% of murine hepatitis coronaviruses (SARS-CoV surrogate) and clinical isolates of methicillin-resistant Staphylococcus aureus within 2 min. Direct surface contact was experimentally verified as the mechanism of action, whereby the coating induced the disruption of the bacterial cell membrane. More notably, the coating also exhibited other excellent properties, including colorless appearance, high durability to various post-treatments, excellent skin compatibility, and ease of industrial scale-up, making it a promising technology to prevent the spread of nosocomial infections and enhance our preparedness against global outbreaks of infectious diseases in the future.

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ACS Applied Engineering Materials 材料科学-

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期刊介绍： ACS Applied Engineering Materials is an international and interdisciplinary forum devoted to original research covering all aspects of engineered materials complementing the ACS Applied Materials portfolio. Papers that describe theory simulation modeling or machine learning assisted design of materials and that provide new insights into engineering applications are welcomed. The journal also considers experimental research that includes novel methods of preparing characterizing and evaluating new materials designed for timely applications. With its focus on innovative applications ACS Applied Engineering Materials also complements and expands the scope of existing ACS publications that focus on materials science discovery including Biomacromolecules Chemistry of Materials Crystal Growth & Design Industrial & Engineering Chemistry Research Inorganic Chemistry Langmuir and Macromolecules.The scope of ACS Applied Engineering Materials includes high quality research of an applied nature that integrates knowledge in materials science engineering physics mechanics and chemistry.