Prenatal Diagnostics Using Deep Learning: A Dual Approach to Plane Localization and Cerebellum Segmentation in Ultrasound Images.

Abstract

Objective: The fetal ultrasound examination is the significant task of mid-term pregnancy inspection and the accurate localization as well as the segmentation of the cerebellum is crucial for clinical diagnosis. This research focuses on developing deep learning techniques for prenatal prediction of neurodevelopmental disorders using 5th-month ultrasound brain images.

Methods: The study introduces two specialized convolutional neural network (CNN) architectures: the differential CNN for plane localization and the dual CNN for cerebellum segmentation which are critical for accurate diagnostics during prenatal care. The differential CNN incorporates six different convolutional operators to capture diverse features for precise localization of specific planes within images. The dual CNN architecture integrates both the original image and complementary information such as feature maps, to enhance segmentation accuracy for the cerebellum. The models are trained on annotated datasets of ultrasound images, validated, and tested on separate datasets.

Results: The effectiveness of the proposed CNN architectures is determined by performing the specific tasks of plane localization and cerebellum segmentation, respectively. The proposed models achieved high performances of 98.6% and 0.956% from accuracy and dice coefficient (DSC) compared to existing approaches in medical image analysis.

Conclusion: The findings of this study have significant implications for the prenatal prediction of neurodevelopmental disorders, offering a promising advancement in prenatal care and early diagnostics. The custom CNN architectures tailored to the specific tasks of plane localization and cerebellum segmentation highlight the importance of task-specific model design in medical imaging. While the study acknowledges certain limitations and challenges, the power of deep learning is analyzed for marking the benefit of healthcare and neurodevelopmental disorder prediction during pregnancy.