{"title":"Review on the Phytochemistry and Pharmacological Potential of Saffron (Crocus sativus L.).","authors":"Sonia Singh, Khushi Sharma","doi":"10.2174/0115680266352428250130112654","DOIUrl":null,"url":null,"abstract":"<p><p>Saffron has been used in Chinese medicine for a very long time, dating back to 1979, when it was first brought inside of China. According to Traditional Chinese medicine, saffron has a sweet, moderately chilly character, and it has remarkable effects on the liver and heart systems. In addition, this spice stimulates blood circulation, removes blood stasis, reduces blood temperature, and eradicates heat-related toxins. The herb has been used to treat a variety of conditions, including pain, hemoptysis, asthma, phlegm, sleeplessness, depression, anxiety, and Alzheimer's disease. Saffron has over seventy different bioactive components, the most important of which are crocin, crocetin, and safranal. These three components are responsible for the distinctive color and flavor of saffron. This article briefly covers the phytochemistry and pharmacological potential of this uncommon herb.</p>","PeriodicalId":11076,"journal":{"name":"Current topics in medicinal chemistry","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current topics in medicinal chemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/0115680266352428250130112654","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Saffron has been used in Chinese medicine for a very long time, dating back to 1979, when it was first brought inside of China. According to Traditional Chinese medicine, saffron has a sweet, moderately chilly character, and it has remarkable effects on the liver and heart systems. In addition, this spice stimulates blood circulation, removes blood stasis, reduces blood temperature, and eradicates heat-related toxins. The herb has been used to treat a variety of conditions, including pain, hemoptysis, asthma, phlegm, sleeplessness, depression, anxiety, and Alzheimer's disease. Saffron has over seventy different bioactive components, the most important of which are crocin, crocetin, and safranal. These three components are responsible for the distinctive color and flavor of saffron. This article briefly covers the phytochemistry and pharmacological potential of this uncommon herb.
期刊介绍：
Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.
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