pH-Dependant Electrochemical Oxidation of Small Molecules on Glassy Carbon, Platinum and Gold

Abstract

Composite electrodes often consisting of a purportedly inactive support material modified with a variety of nanomaterials, surface chemistry and coatings are commonly employed as electroanalytical devices for detection of biologically relevant molecules. However, these electrodes are often used in various electrolytes and biological fluids treated in a variety of ways making comparisons between materials difficult. Additionally, nanomaterial designers have developed techniques capable of controlling the local solution environment at the interface of electrodes. Herein, we present a study of the electro-oxidation of glucose, ascorbic acid, uric acid and dopamine on glassy carbon, platinum and gold. Peak potential and current versus pH are presented to provide a database and resource to aid in the deconvolution of the electrochemical response produced by these materials. Additionally, in light of recent developments in pH control within nanoconfined electrodes, a study of how altering the pH of an electrolyte allows for the separation of previously overlapping peaks is presented.