Gold-Catalyzed Highly Regioselective Hydration of Alkynylsulfonamides for Atom-Economic Synthesis of N-Ketosulfonamides

IF 3.7 2区化学 Q2 CHEMISTRY, APPLIED

Applied Organometallic Chemistry Pub Date : 2025-01-21 DOI:10.1002/aoc.70003

Yuguang Wang, Menghao Ma, Yunlong Deng, Panpan Yao, Agui Xing, Wenjing Li, Yuan Chen, Ji'an Wu

引用次数: 0

Abstract

Gold(I)-catalyzed highly regioselective hydration of alkynylsulfonamides for synthesis of N-ketosulfonamides in 85%–96% yields. The reaction used water as a nucleophile, which had the advantages of mild reaction conditions, good functional group tolerance, high regioselectivity, high yield, and 100% atomic economy (without generating by-products or waste). This might endow this method with great potential in green synthesis of N-ketosulfonamides compounds.

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金（I）催化炔基磺酰胺的高区域选择性水合反应，以 85%-96% 的产率合成 N-酮基磺酰胺。该反应以水为亲核体，具有反应条件温和、官能团耐受性好、高区域选择性、高产率和 100% 原子经济性（不产生副产物或废物）等优点。这可能赋予该方法在绿色合成 N-酮基磺酰胺类化合物方面的巨大潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Organometallic Chemistry 化学-无机化学与核化学

CiteScore

7.80

自引率

10.30%

发文量

408

审稿时长

2.2 months

期刊介绍： All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.