Information System Security (ISS) is the primary economic lever for the global economy. It is the cornerstone for value generation, and its absence undeniably affects technology, people, and finances. The emergence of the worldwide information society has introduced fresh economic and legal challenges attributed to the surge in Internet utilization and advancements in the digital economy. Ensuring the security of advancements within information systems has emerged as a primary concern in propelling the evolution of information processes within the software development industry. This study aims to develop and propose a Fuzzy Analytic Hierarchy Process (Fuzzy-AHP) framework to enhance decision-making for software maintenance and deployment in ISS. This framework aims to provide a systematic, flexible method for evaluating and prioritizing multiple conflicting criteria under conditions of uncertainty. The study initially adopts an empirical survey to identify software security maintenance and deployment risks and their practices for ISS organizations. Then adopts the Fuzzy-AHP method to handle the imprecision of expert judgments and organizes decision-making into a hierarchical structure. The framework is applied to evaluate key criteria related to software maintenance and deployment, including security risks, system performance, operational costs, and compliance requirements. Data from 50 ISS experts were collected and used to validate the framework. The paper identifies 52 security risks in maintenance and deployment (SRMD) processes in ISS and also identified 139 best practices for ensuring security, including regular updates, patch management, and adherence to industry-standard security protocols. The Fuzzy-AHP framework effectively structured the decision-making process by prioritizing criteria and sub-criteria. The results demonstrated that the framework helps mitigate the subjective biases in expert judgment and provides a more balanced assessment of maintenance and deployment strategies. Prioritizing security risks and compliance emerged as key factors in the decision-making process. The proposed Fuzzy-AHP framework provides an innovative and adaptable solution for optimizing ISS organizations' software maintenance and deployment decisions. It addresses the complexity and uncertainty involved in such decisions, offering a transparent and structured approach that improves the accuracy and reliability of outcomes. Future research should focus on empirical validation of the framework in real-world case studies and expand its application to other industries with similar decision-making needs.